Cognitive functioning in patients with complex absence following treatment with sodium valproate
The association of sodium valproate with cognitive functions was studied in 29 patients with complex absence seizures. Seventeen patients were on monotherapy and twelve on polypharmacy with sodium valproate. Cognitive functions assessed were attention, speech, visuo-speciat perception, memory and in...
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| Published in | Indian journal of psychiatry Vol. 35; no. 1; pp. 54 - 57 |
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| Main Authors | , , |
| Format | Journal Article |
| Language | English |
| Published |
India
Medknow Publications
01.01.1993
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| Subjects | |
| Online Access | Get full text |
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| Abstract | The association of sodium valproate with cognitive functions was studied in 29 patients with complex absence seizures. Seventeen patients were on monotherapy and twelve on polypharmacy with sodium valproate. Cognitive functions assessed were attention, speech, visuo-speciat perception, memory and intelligence. Behavioral disturbances were also assessed. Two assessments were made six months apart; in the first assessment, attention and speech were adequate, while memory, visuo-spatial perception, and behavioral functioning were impaired. Intelligence was lower in the polypharmacy group, while other functions were similar. In the second assessment, intelligence and visual memory improved in the monotherapy group, while no changes were present in the polypharmacy group. |
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| AbstractList | The association of sodium valproate with cognitive functions was studied in 29 patients with complex absence seizures. Seventeen patients were on monotherapy and twelve on polypharmacy with sodium valproate. Cognitive functions assessed were attention, speech, visuo-speciat perception, memory and intelligence. Behavioral disturbances were also assessed. Two assessments were made six months apart; in the first assessment, attention and speech were adequate, while memory, visuo-spatial perception, and behavioral functioning were impaired. Intelligence was lower in the polypharmacy group, while other functions were similar. In the second assessment, intelligence and visual memory improved in the monotherapy group, while no changes were present in the polypharmacy group. |
| Author | Devi, M G Rao, S L Satischandra, P |
| AuthorAffiliation | Associate Professor of Neurology, National Institute of Mental Health and Neuro Sciences, Bangalore - 560 029 Associate Professor of Clinical Psychology, National Institute of Mental Health and Neuro Sciences, Bangalore - 560 029 Professor of Neurology, National Institute of Mental Health and Neuro Sciences, Bangalore - 560 029 |
| AuthorAffiliation_xml | – name: Associate Professor of Clinical Psychology, National Institute of Mental Health and Neuro Sciences, Bangalore - 560 029 – name: Professor of Neurology, National Institute of Mental Health and Neuro Sciences, Bangalore - 560 029 – name: Associate Professor of Neurology, National Institute of Mental Health and Neuro Sciences, Bangalore - 560 029 |
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| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/21776171$$D View this record in MEDLINE/PubMed |
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| Copyright | Copyright: © Indian Journal of Psychiatry 1993 |
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| Title | Cognitive functioning in patients with complex absence following treatment with sodium valproate |
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