Pathological findings in very low risk prostate cancer in surgical specimens

Perform a detailed anatomopathological analysis of consecutive surgical specimens in men with clinically very low risk prostate cancer according to National Comprehensive Cancer Network (NCCN) criteria.MATERIALS AND METHODS: The study included 799 prostate cancer patients who under went radical pros...

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Published inArchivos españoles de urología Vol. 73; no. 7; p. 593
Main Authors Tamayo-Jover, Marco Antonio, González Álvarez, Ruiman José, Nazco Deroy, Ángel, Plata Bello, Ana Cristina, Álvarez-Arguelles, Hugo, García Álvarez, Carlos, Jimenez Sosa, Alejandro, Castro-Díaz, David Manuel, Concepción Masip, Tomás
Format Journal Article
LanguageEnglish
Published Spain 01.09.2020
Subjects
Humans
Male
Neoplasm Grading
Neoplasm Staging
Prostate-Specific Antigen
Prostatectomy
Prostatic Neoplasms
Cáncer de próstata
Active surveillance
Prostatic neoplasms
Muy bajo riesgo
Próstata
Very low risk
Neoplasia prostática
Riesgo
Risk
Vigilancia activa
Prostate
Prostate cancer
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Summary:Perform a detailed anatomopathological analysis of consecutive surgical specimens in men with clinically very low risk prostate cancer according to National Comprehensive Cancer Network (NCCN) criteria.MATERIALS AND METHODS: The study included 799 prostate cancer patients who under went radical prostatectomy between January 2005 and December 2013. We identified 81 consecutive patients with clinically very low risk prostate cancer. The slides of the patients who fulfilled the inclusion criteria were re-reviewed. The parameters studied were: pathological stage, histological grade by Gleason score (GSS), margins involvement, tumor percentage (PT), and number of apparently independent tumor foci (FT). RESULTS: The patients had organ-confined tumors in almost all of them (pT2: 97.5%). Most of the cancers studied were bilateral (pT2c: 67.9%), multifocal (FT≥2:88.8%), with a low tumor percentage (PTand with a low Gleason Score (GSS≤6: 91,3%). Non-confined disease: 2.5%, all cases extra-prostatic extension (pT3a). GSS>6: 8,6%, all cases GSS7 (3+4). CONCLUSIONS: The NCCN criteria for very low risk prostate cancer help to make a good selection of non-aggressive tumors and are a useful tool for including patients in an active surveillance program.
ISSN:0004-0614
1576-8260