Thrombolysis in acute ischemic stroke in centers lacking a stroke unit: referral to reference center or on-site treatment?

• Published in: Medicina intensiva Vol. 36; no. 5; p. 324
• Main Authors: Latour-Pérez, J, Galdos Anuncibay, P
• Format: Journal Article
• Language: Spanish
• Published: Spain 01.06.2012
• Subjects: Brain Damage, Chronic - epidemiology; Brain Damage, Chronic - etiology; Brain Damage, Chronic - prevention & control; Brain Ischemia - drug therapy; Cohort Studies; Computer Simulation; Decision Trees; Fibrinolytic Agents - administration & dosage; Fibrinolytic Agents - therapeutic use; Follow-Up Studies; Hospital Units; Humans; Meta-Analysis as Topic; Models, Theoretical; Patient Transfer; Randomized Controlled Trials as Topic - statistics & numerical data; Referral and Consultation; Thrombolytic Therapy; Time Factors; Treatment Outcome

To assess the clinical impact of on-site thrombolysis versus referral to another hospital in patients with ischemic stroke attended in a hospital lacking a stroke unit. Expected value decision analysis and Monte Carlo simulation. Decision analysis based on a cohort study (SIT-MOST) and a meta-analys...