Detection of erectile dysfunction and peculiarities of its treatment in men with high cardiovascular risk
It has been demonstrated in a series of studies that erectile dysfunction (ED) appears to be one of risk factors and predictors of ischemic heart disease (IHD). According to the SSRC PM data in a cohort of 300 men with high cardiovascular risk ED was diagnosed in 61% of cases, while among 300 men wi...
Saved in:
Published in | Kardiologiia Vol. 50; no. 11; p. 85 |
---|---|
Main Authors | , , , , , |
Format | Journal Article |
Language | Russian |
Published |
Russia (Federation)
2010
|
Subjects | |
Online Access | Get more information |
Cover
Loading…
Abstract | It has been demonstrated in a series of studies that erectile dysfunction (ED) appears to be one of risk factors and predictors of ischemic heart disease (IHD). According to the SSRC PM data in a cohort of 300 men with high cardiovascular risk ED was diagnosed in 61% of cases, while among 300 men with verified diagnosis of IHD was detected in 92.7% of cases. According to recommendations of the European Society of Urology changes of life style and correction of risk factors should precede therapy of ED or be components of complex therapy. It is known that some antihypertensive drugs (nonselective beta-adrenoblockers, thiazide diuretics) can negatively affect erectile function. According to data of comparative randomized clinical study average therapeutic doses of thiazide-like and thiazide diuretics in combination with ACE inhibitors do not worsen erectile function. Data on effect of lipid lowering therapy on erectile function are equivocal. Type 5 phosphodiesterase inhibitors (PDI) are first line preparations for the treatment of patients with ED. Safety of combination of type 5 PDI with main groups of antihypertensive drugs has been demonstrated in persons with risk factors of CVD and ED. The use of type 5 PDI in men depends on degree of compensation of cardiovascular system. In unstable cardiovascular events preparations of this group can be also carefully used. Simultaneous administration of nitrates is a contraindication for type 5 PDI. |
---|---|
AbstractList | It has been demonstrated in a series of studies that erectile dysfunction (ED) appears to be one of risk factors and predictors of ischemic heart disease (IHD). According to the SSRC PM data in a cohort of 300 men with high cardiovascular risk ED was diagnosed in 61% of cases, while among 300 men with verified diagnosis of IHD was detected in 92.7% of cases. According to recommendations of the European Society of Urology changes of life style and correction of risk factors should precede therapy of ED or be components of complex therapy. It is known that some antihypertensive drugs (nonselective beta-adrenoblockers, thiazide diuretics) can negatively affect erectile function. According to data of comparative randomized clinical study average therapeutic doses of thiazide-like and thiazide diuretics in combination with ACE inhibitors do not worsen erectile function. Data on effect of lipid lowering therapy on erectile function are equivocal. Type 5 phosphodiesterase inhibitors (PDI) are first line preparations for the treatment of patients with ED. Safety of combination of type 5 PDI with main groups of antihypertensive drugs has been demonstrated in persons with risk factors of CVD and ED. The use of type 5 PDI in men depends on degree of compensation of cardiovascular system. In unstable cardiovascular events preparations of this group can be also carefully used. Simultaneous administration of nitrates is a contraindication for type 5 PDI. |
Author | Sharvadze, G G Digigova, R T Mamedov, M N Stroeva, M V Ugurchieva, Z O Kovrigina, M N |
Author_xml | – sequence: 1 givenname: M N surname: Mamedov fullname: Mamedov, M N – sequence: 2 givenname: R T surname: Digigova fullname: Digigova, R T – sequence: 3 givenname: G G surname: Sharvadze fullname: Sharvadze, G G – sequence: 4 givenname: Z O surname: Ugurchieva fullname: Ugurchieva, Z O – sequence: 5 givenname: M N surname: Kovrigina fullname: Kovrigina, M N – sequence: 6 givenname: M V surname: Stroeva fullname: Stroeva, M V |
BackLink | https://www.ncbi.nlm.nih.gov/pubmed/21526570$$D View this record in MEDLINE/PubMed |
BookMark | eNo1T8tqwzAQ1CGlSdP8QtEPGNaK5NjHkj4h0Et7Dnqs6qW2bCS5JX9fh7RzmZ1hZmFu2CIMARdsBSBE0YCEJdukRAagUrutVOqaLUWpxKxgxegBM9pMQ-CD5xjPd4fcnZKfwsXXwfER7dSRjpQJ0zlJOfEcUeceQ-YU-Mz8h3LLW_psudXR0fCt01zTkUdKX7fsyusu4eaP1-zj6fF9_1Ic3p5f9_eHYiwl5AKhkb6UToKBra7QatkIo4xVzle-NkJpbGTtyxnO18I5gBItgLJCNzsh1uzu8necTI_uOEbqdTwd_zeLXx3DVto |
ContentType | Journal Article |
DBID | CGR CUY CVF ECM EIF NPM |
DatabaseName | Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed |
DatabaseTitle | MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) |
DatabaseTitleList | MEDLINE |
Database_xml | – sequence: 1 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database |
DeliveryMethod | no_fulltext_linktorsrc |
ExternalDocumentID | 21526570 |
Genre | Journal Article Review |
GroupedDBID | ALMA_UNASSIGNED_HOLDINGS CGR CUY CVF ECM EIF NPM OK1 |
ID | FETCH-LOGICAL-p140t-e094f14d40b03a6eca492b5bc5df6f8b25ae948f1111df82dd001ec005c2a9722 |
ISSN | 0022-9040 |
IngestDate | Tue Jul 04 17:16:49 EDT 2023 |
IsPeerReviewed | true |
IsScholarly | true |
Issue | 11 |
Language | Russian |
LinkModel | OpenURL |
MergedId | FETCHMERGED-LOGICAL-p140t-e094f14d40b03a6eca492b5bc5df6f8b25ae948f1111df82dd001ec005c2a9722 |
PMID | 21526570 |
ParticipantIDs | pubmed_primary_21526570 |
PublicationCentury | 2000 |
PublicationDate | 2010-00-00 |
PublicationDateYYYYMMDD | 2010-01-01 |
PublicationDate_xml | – year: 2010 text: 2010-00-00 |
PublicationDecade | 2010 |
PublicationPlace | Russia (Federation) |
PublicationPlace_xml | – name: Russia (Federation) |
PublicationTitle | Kardiologiia |
PublicationTitleAlternate | Kardiologiia |
PublicationYear | 2010 |
SSID | ssib006573455 ssib004297270 ssib001187544 ssib046627731 ssib015894317 ssib000829751 ssib002807064 |
Score | 1.7897909 |
SecondaryResourceType | review_article |
Snippet | It has been demonstrated in a series of studies that erectile dysfunction (ED) appears to be one of risk factors and predictors of ischemic heart disease... |
SourceID | pubmed |
SourceType | Index Database |
StartPage | 85 |
SubjectTerms | Adrenergic beta-Antagonists - administration & dosage Adrenergic beta-Antagonists - adverse effects Angiotensin-Converting Enzyme Inhibitors - administration & dosage Angiotensin-Converting Enzyme Inhibitors - adverse effects Atherosclerosis - complications Atherosclerosis - metabolism Atherosclerosis - physiopathology Cardiovascular Diseases - drug therapy Cardiovascular Diseases - etiology Cardiovascular Diseases - metabolism Cardiovascular Diseases - physiopathology Cardiovascular Diseases - psychology Clinical Trials as Topic Contraindications Depression - etiology Depression - physiopathology Drug Interactions Drug Therapy, Combination Erectile Dysfunction - drug therapy Erectile Dysfunction - etiology Erectile Dysfunction - metabolism Erectile Dysfunction - physiopathology Erectile Dysfunction - psychology Humans Life Style Male Nitroglycerin - administration & dosage Nitroglycerin - adverse effects Penile Erection - drug effects Phosphodiesterase 5 Inhibitors - administration & dosage Phosphodiesterase 5 Inhibitors - adverse effects Risk Factors Sodium Chloride Symporter Inhibitors - administration & dosage Sodium Chloride Symporter Inhibitors - adverse effects |
Title | Detection of erectile dysfunction and peculiarities of its treatment in men with high cardiovascular risk |
URI | https://www.ncbi.nlm.nih.gov/pubmed/21526570 |
Volume | 50 |
hasFullText | |
inHoldings | 1 |
isFullTextHit | |
isPrint | |
link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV3JbsIwELW6XHqpWnXf5ENvKBUxTkiOVWmLWkEvIKFeUBLbKAcWQVqpfH1nbEwMatXlElAcLOR5jGfMvDeEXCuGzRTi0AtTpjyu4poXK4E0rgB2_8xP6pq31mqHzS5_6gW9kq6o2SVFepPNv-SV_MeqcA_siizZP1h2OSncgPdgX7iCheH6Kxs3ZCEzG_JJ7buQB_Uxw92qsIXGE-x_mydTrZ1qFGZnToF5PqoMF2TuCooXo1i1W6KKxeduCPush9Fl5kuX3kpgUx2_69PV8s-dRj7IBzCRNmPFUYPEfkRiro9SH8vmXt0BNqbKpfnAa-XFPZHQhW32RKJkCMRVI8NkvayRl7Vo8h2faVr2OOaaDLW9sOMuFub8PLqmmG2HNslmPUKv13ZPcDSX2JW8i1AD0ElBwQm6ivvwOHN8Gkxc4yWX1w9QwL5METkK6tdNG0y7DFpw2nylteRFBzGdPbK7yD7orYHSPtmYvh2QfAkjOlbUwog6MKIAI7oCI3wSYESXMKL5iMIrRRhRhBFdhRFFGB2S7sN9567pLTpweBNIvAtPQvKvfC54Na3WklBmCY9ZGqRZIFSoopQFiYx5pHDfFSpiQsCCygw8e8YSWDd2RLZG45E8IZTFGYTyicACfS7BKUCqzH1sJlCLpaiHp-TYrEx_YmRW-nbNzr4dOSc7Jf4uyLaC37W8hCCxSK-01T8BdlVhpw |
link.rule.ids | 786 |
linkProvider | National Library of Medicine |
openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Detection+of+erectile+dysfunction+and+peculiarities+of+its+treatment+in+men+with+high+cardiovascular+risk&rft.jtitle=Kardiologiia&rft.au=Mamedov%2C+M+N&rft.au=Digigova%2C+R+T&rft.au=Sharvadze%2C+G+G&rft.au=Ugurchieva%2C+Z+O&rft.date=2010-01-01&rft.issn=0022-9040&rft.volume=50&rft.issue=11&rft.spage=85&rft_id=info%3Apmid%2F21526570&rft_id=info%3Apmid%2F21526570&rft.externalDocID=21526570 |
thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0022-9040&client=summon |
thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0022-9040&client=summon |
thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0022-9040&client=summon |