Tunnelled internal jugular vein catheters with taurolidine lock: an acceptable challenge to arterio-venous fistula in 70 years old haemodialyzed patients: a prospective pilot study

• Published in: Néphrologie & thérapeutique Vol. 7; no. 4; pp. 237 - 241
• Main Authors: Branger, Bernard, Reboul, Pascal, Prelipcean, Camélia, Noguera, Maria Eugenia, Cariou, Sylvain, Granolleras, Céline, Vecina, Frédérique, Zabadani, Bachir, Boubenider, Samir, Rousseau, Philippe, Deshodt, Gérard, Ramperez, Pierre, Hory, Bernard, Picard, Eric, Branchereau, Pascal, Fabbro-Peray, Pascale, Fourcade, Jacques
• Format: Journal Article
• Language: French
• Published: France 01.07.2011
• Subjects: Aged; Anti-Infective Agents, Local - therapeutic use; Arteriovenous Shunt, Surgical - methods; Catheterization, Central Venous; Catheters, Indwelling; Female; Humans; Jugular Veins; Kidney Failure, Chronic - therapy; Male; Pilot Projects; Prospective Studies; Renal Dialysis - methods; Taurine - analogs & derivatives; Taurine - therapeutic use; Thiadiazines - therapeutic use; Treatment Outcome
• DOI: 10.1016/j.nephro.2011.04.001

Arteriovenous fistula (AVF) is still in 2010 the gold standard of vascular(2) access in haemodialysis (HD) patients. Nevertheless it may be difficult to obtain and/or to use AVF in elderly. With this prospective randomised pilot study, we compare two strategies of vascular access in 70 years old or more new HD patients. AVF were compared to tunnelled jugular vein catheters (TIJC) with taurolidine as bacterial lock solution. Results were as follow: [table: see text] The responses with the visual analogic scale of comfort was 8/10 for TIJC and 5/10 with AVF * P<0.05. In five TIJC patients, heparin was added with success to taurolidine because of partial clotting of catheters. Albuminemia was significantly lower in AVF failure patients compared to AVF success patients (24.8g/L vs 31.1g/L). This pilot study allows to conclude that TIJC is an acceptable challenge to AVF in haemodialysed patients of 70 years or more in a two years long use.