Metabolic disorders under antipsychotic treatment

Patients with severe mental illness, such as schizophrenia, depression or bipolar disorder, are more likely to be overweight and to suffer from dyslipidaemia, diabetes or cardiovascular disease. Unhealthy lifestyles, including poor diet and sedentary behaviour, but also pharmacotherapy contribute to...

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Bibliographic Details
Published inNervenarzt Vol. 83; no. 3; p. 337
Main Authors Steffenhagen, N, Rummel-Kluge, C, Himmerich, H
Format Journal Article
LanguageGerman
Published Germany 01.03.2012
Subjects
Antipsychotic Agents - adverse effects
Germany
Humans
Metabolic Diseases - chemically induced
Metabolic Diseases - epidemiology
Prevalence
Risk Assessment
Risk Factors
Germany
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Summary:Patients with severe mental illness, such as schizophrenia, depression or bipolar disorder, are more likely to be overweight and to suffer from dyslipidaemia, diabetes or cardiovascular disease. Unhealthy lifestyles, including poor diet and sedentary behaviour, but also pharmacotherapy contribute to the adverse risk profile. This article reviews the epidemiology and pharmacodynamics of metabolic abnormalities in psychiatric patients treated with antipsychotics, focusing on substance-specific differences.
ISSN:1433-0407
DOI:10.1007/s00115-010-3207-1