Dialysis modality-dependent changes in serum metabolites: accumulation of inosine and hypoxanthine in patients on haemodialysis

• Published in: Nephrology, dialysis, transplantation Vol. 26; no. 4; p. 1304
• Main Authors: Choi, Ji-Young, Yoon, Yoo Jeong, Choi, Hee-Jeong, Park, Sun-Hee, Kim, Chan-Duck, Kim, In-San, Kwon, Tae-Hwan, Do, Jun-Young, Kim, Sung-Ho, Ryu, Do Hyun, Hwang, Geum-Sook, Kim, Yong-Lim
• Format: Journal Article
• Language: English
• Published: England 01.04.2011
• Subjects: Case-Control Studies; Creatinine - blood; Female; Humans; Hypoxanthine - blood; Inosine - blood; Kidney Failure, Chronic - blood; Kidney Failure, Chronic - therapy; Magnetic Resonance Spectroscopy; Male; Metabolomics; Middle Aged; Peritoneal Dialysis; Principal Component Analysis; Renal Dialysis; Xanthine Oxidase - blood

The body metabolism of patients with end-stage renal disease may be altered in response to long-term dialysis treatment. Moreover, the pattern of serum metabolites could change depending on the type of dialysis modality used. However, dialysis modality-dependent changes in serum metabolites are poor...