Congenital self healing reticulohistiocytosis in a newborn (Hashimoto Pritzker)

• Published in: Anais brasileiros de dermatología Vol. 86; no. 4; pp. 785 - 788
• Main Authors: Orle, Joana, Mósca, Ana Maria, Sousa, Maria Auxiliadora Jeunon, Lima, Cíntia Maria Oliveira, Adriano, André Ricardo, Rezende, Patrícia Makino
• Format: Journal Article
• Language: English; Portuguese
• Published: Brazil 01.07.2011
• Subjects: Antigens, CD1 - analysis; Histiocytosis, Langerhans-Cell - congenital; Histiocytosis, Langerhans-Cell - diagnosis; Humans; Immunohistochemistry; Infant, Newborn; Male; Remission, Spontaneous; S100 Proteins - analysis
• DOI: 10.1590/S0365-05962011000400026

Congenital self-healing reticulohistiocytosis is the benign spectrum of Langerhans Cell Histiocytosis, characterized by cutaneous lesions at birth or in the neonatal period, absence of systemic manifestations and spontaneous resolution of clinical status. Despite the benign and often self-resolving course in most patients, studies show that in some cases there may be metastasis or recurrence of the disease, emphasizing that the clinical course is variable, requiring long-term follow-up. The monitoring of the patient for a long period is important to detect possible systemic involvement, as there is a report of recurrence involving the skin, mucosa, bone and pituitary gland.