Congenital self healing reticulohistiocytosis in a newborn (Hashimoto Pritzker)

Congenital self-healing reticulohistiocytosis is the benign spectrum of Langerhans Cell Histiocytosis, characterized by cutaneous lesions at birth or in the neonatal period, absence of systemic manifestations and spontaneous resolution of clinical status. Despite the benign and often self-resolving...

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Published inAnais brasileiros de dermatología Vol. 86; no. 4; pp. 785 - 788
Main Authors Orle, Joana, Mósca, Ana Maria, Sousa, Maria Auxiliadora Jeunon, Lima, Cíntia Maria Oliveira, Adriano, André Ricardo, Rezende, Patrícia Makino
Format Journal Article
LanguageEnglish
Portuguese
Published Brazil 01.07.2011
Subjects
Antigens, CD1 - analysis
Histiocytosis, Langerhans-Cell - congenital
Histiocytosis, Langerhans-Cell - diagnosis
Humans
Immunohistochemistry
Infant, Newborn
Male
Remission, Spontaneous
S100 Proteins - analysis
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Summary:Congenital self-healing reticulohistiocytosis is the benign spectrum of Langerhans Cell Histiocytosis, characterized by cutaneous lesions at birth or in the neonatal period, absence of systemic manifestations and spontaneous resolution of clinical status. Despite the benign and often self-resolving course in most patients, studies show that in some cases there may be metastasis or recurrence of the disease, emphasizing that the clinical course is variable, requiring long-term follow-up. The monitoring of the patient for a long period is important to detect possible systemic involvement, as there is a report of recurrence involving the skin, mucosa, bone and pituitary gland.
Bibliography:ObjectType-Case Study-2
SourceType-Scholarly Journals-1
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ISSN:1806-4841
DOI:10.1590/S0365-05962011000400026