Oxidative Stress and Toxicity in Reproductive Biology and Medicine: Historical Perspectives and Future Horizons in Male Fertility

• Published in: Advances in experimental medicine and biology Vol. 1358; p. 1
• Main Author: Henkel, Ralf
• Format: Journal Article
• Language: English
• Published: United States 2022
• Subjects: Antioxidants; Sperm functions; Oxidative stress; Reductive stress; Fertilization

Since the discovery by John MacLeod in 1943 that spermatozoa produce small amounts of hydrogen peroxide, a member of the so-called reactive oxygen species (ROS), the importance and functions of these highly reactive oxygen derivatives in physiology and pathology are a subject of numerous studies. It...