Effect of renin-angiotensin system in Fabry disease associated proteinuria

• Published in: Revista clínica espanõla Vol. 207; no. 3; p. 125
• Main Authors: Pagán Muñoz, B, López-Rodríguez, M, Gómez Cerezo, J F, Poyatos Toribio, C, Barbado Hernández, F J
• Format: Journal Article
• Language: Spanish
• Published: Spain 01.03.2007
• Subjects: Adult; Angiotensin-Converting Enzyme Inhibitors - therapeutic use; Fabry Disease - complications; Fabry Disease - drug therapy; Fabry Disease - epidemiology; Female; Humans; Male; Middle Aged; Prevalence; Proteinuria - drug therapy; Proteinuria - epidemiology; Proteinuria - etiology; Renin-Angiotensin System - physiology

To describe the prevalence of renal involvement in Fabry disease patients and determine the role of ACE inhibitors in its treatment. We studied a family of eight members, diagnosed of Fabry disease after demonstrating alpha-galactosidase deficiency and genetic mutation. Serial biochemical analyses w...