Reconstruction of extensive soft tissue loss by transplantation of dermal and epidermal equivalents

• Published in: Zentralblatt für Chirurgie Vol. 129; no. 1; p. 29
• Main Authors: Hollander, D A, Gutt, C N, Falk, S, Windolf, J, Erli, H J, Paar, O
• Format: Journal Article
• Language: German
• Published: Germany 01.01.2004
• Subjects: Adult; Aged; Biomechanical Phenomena; Biopsy; Child; Culture Techniques; Debridement; Dermatologic Surgical Procedures; Elasticity; Female; Fibroblasts - cytology; Fibroblasts - transplantation; Follow-Up Studies; Granulation Tissue - pathology; Granulation Tissue - physiopathology; Humans; Hyaluronic Acid; Keratinocytes - cytology; Keratinocytes - transplantation; Male; Microsurgery; Middle Aged; Skin - pathology; Skin Transplantation - pathology; Skin Transplantation - physiology; Soft Tissue Injuries - pathology; Soft Tissue Injuries - surgery; Surgical Flaps - blood supply; Surgical Flaps - pathology; Surgical Flaps - physiology; Surgical Mesh; Tissue Engineering; Wound Healing - physiology

The opportunities of autologous dermal and epidermal grafting as starting point for non-invasive reconstruction of extensive soft tissue defects will be demonstrated and discussed. Skin biopsies for cell cultivation were taken from patients with extensive acute soft tissue defects of different origi...