Juçara ( Euterpe edulis Mart.) Supplementation Reduces Aberrant Crypt Foci and Increases SOD1 Expression in the Colorectal Mucosa of Carcinogenesis-Induced Rats

• Published in: Nutrition and cancer Vol. 72; no. 4; pp. 610 - 619
• Main Authors: Dos Reis, Schalana Oliveira, da Luz, Tamires Conceição, da Silva Couto, Cinthia Vidal Monteiro, Dalbó, Juliana, Nunes, Louisiane de Carvalho, Martins, Marina Carvalho, Silva, Pollyanna Ibrahim, da Silva, Adriana Madeira Alvares, Trivilin, Leonardo Oliveira
• Format: Journal Article
• Language: English
• Published: United States Taylor & Francis Ltd 2020
• Subjects: 1,2-Dimethylhydrazine; Aberrant Crypt Foci - prevention & control; Animals; Antioxidants; Carcinogenesis; Carcinogens; Colon; Colorectal carcinoma; Colorectal Neoplasms - prevention & control; Crypts; Diet; Dietary Supplements; Dimethylhydrazines; Euterpe - chemistry; Female; Food cans; Fruits; Intestinal Mucosa - enzymology; Mucosa; Prevention; Pulp; Rats; Superoxide dismutase; Superoxide Dismutase-1 - genetics; Weight Gain

Antioxidants present in food can act as a protective factor against the development of colorectal cancer (CRC) by reducing the development of aberrant crypt foci (ACF). This study aimed to analyze the effects of supplementation with juçara fruit pulp on the number of ACF and the SOD1 expression in a...