肝硬化并发门静脉血栓的危险因素及中医证候特点
摘要:目的探讨肝硬化门静脉血栓 (PVT) 发生的危险因素及中医证候特点。方法选取2015年1月-2019年3月在上海中医药大学附属曙光医院住院的并发PVT的肝硬化患者62例,同时随机抽取66例无PVT肝硬化患者作为对照。收集并比较两组患者的临床资料。计量资料组间比较采用独立样本t检验或Mann-Whitney U秩和检验,计数资料组间比较采用χ2检验或Fisher精确概率法,多因素分析采用非条件多因素logistic回归。结果单因素分析结果显示,PVT组与无PVT组患者在肝硬化病因 (χ2=12. 902,P=0. 036) 、ALT (Z=-2. 571,P=0. 010) 、AST (Z...
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| Published in | Linchuang gandanbing zazhi Vol. 35; no. 10; pp. 2210 - 2213 |
|---|---|
| Main Authors | , , , , |
| Format | Journal Article |
| Language | Chinese |
| Published |
Changchun
Journal of Clinical Hepatology
01.10.2019
上海中医药大学附属曙光医院肝二科,上海,201203%上海中医药大学肝病研究所,上海,201203%上海中医药大学附属曙光医院肝二科,上海201203 上海中医药大学肝病研究所,上海201203 |
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| Online Access | Get full text |
| ISSN | 1001-5256 2097-3497 |
| DOI | 10.3969/j.issn.1001-5256.2019.10.016 |
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| Abstract | 摘要:目的探讨肝硬化门静脉血栓 (PVT) 发生的危险因素及中医证候特点。方法选取2015年1月-2019年3月在上海中医药大学附属曙光医院住院的并发PVT的肝硬化患者62例,同时随机抽取66例无PVT肝硬化患者作为对照。收集并比较两组患者的临床资料。计量资料组间比较采用独立样本t检验或Mann-Whitney U秩和检验,计数资料组间比较采用χ2检验或Fisher精确概率法,多因素分析采用非条件多因素logistic回归。结果单因素分析结果显示,PVT组与无PVT组患者在肝硬化病因 (χ2=12. 902,P=0. 036) 、ALT (Z=-2. 571,P=0. 010) 、AST (Z=-2. 801,P=0. 005) 、胆碱酯酶 (t=-2. 579,P=0. 011) 、纤维蛋白降解产物 (Z=-4. 410,P <0. 001) 、D-二聚体 (Z=-4. 888,P <0. 001) 、中性粒细胞百分比 (Z=-3. 124,P=0. 002) 、门静脉主干内径 (t=2. 572,P=0. 012) 、门静脉血流速度 (t=-2. 441,P=0. 016) 、脾静脉内径 (t=3. 175,P=0... |
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| AbstractList | R575.2; 目的 探讨肝硬化门静脉血栓(PVT)发生的危险因素及中医证候特点.方法 选取2015年1月-2019年3月在上海中医药大学附属曙光医院住院的并发PVT的肝硬化患者62例,同时随机抽取66例无PVT肝硬化患者作为对照.收集并比较两组患者的临床资料.计量资料组间比较采用独立样本t检验或Mann-Whitney U秩和检验,计数资料组间比较采用χ2检验或Fisher精确概率法,多因素分析采用非条件多因素logistic回归.结果 单因素分析结果显示,PVT组与无PVT组患者在肝硬化病因(χ2=12.902,P=0.036)、ALT(Z=-2.571,P=0.010)、AST(Z=-2.801,P=0.005)、胆碱酯酶(t=-2.579,P=0.011)、纤维蛋白降解产物(Z=-4.410,P<0.001)、D-二聚体(Z=-4.888,P<0.001)、中性粒细胞百分比(Z=-3.124,P=0.002)、门静脉主干内径(t=2.572,P=0.012)、门静脉血流速度(t=-2.441,P=0.016)、脾静脉内径(t=3.175,P=0.002)、脾脏厚径(t=4.575,P<0.001)、脾脏长径(Z=-4.028,P<0.001)和腹腔积液量(t=2.273,P=0.025)等方面差异均有统计学意义;进一步logistic回归分析结果显示,D-二聚体(比值比为2.078,95％置信区间(95％CI):1.293～3.339,P=0.003)、脾脏长径(比值比为1.964,95％CI 1.228～3.142,P=0.005)是肝硬化并发PVT的独立危险因素;乏力(100％)、脾大(74.19％)、腹胀(46.77％)、食管胃静脉曲张重度(48.29％)、静脉曲张出血史(40.32％)、舌淡红(43.55％)、脉弦/细(96.77％)是肝硬化并发PVT患者的主要特征.结论 D-二聚体水平升高、脾脏长径长是肝硬化并发PVT的独立危险因素,其证候特点符合气虚血瘀证表现. 摘要:目的探讨肝硬化门静脉血栓 (PVT) 发生的危险因素及中医证候特点。方法选取2015年1月-2019年3月在上海中医药大学附属曙光医院住院的并发PVT的肝硬化患者62例,同时随机抽取66例无PVT肝硬化患者作为对照。收集并比较两组患者的临床资料。计量资料组间比较采用独立样本t检验或Mann-Whitney U秩和检验,计数资料组间比较采用χ2检验或Fisher精确概率法,多因素分析采用非条件多因素logistic回归。结果单因素分析结果显示,PVT组与无PVT组患者在肝硬化病因 (χ2=12. 902,P=0. 036) 、ALT (Z=-2. 571,P=0. 010) 、AST (Z=-2. 801,P=0. 005) 、胆碱酯酶 (t=-2. 579,P=0. 011) 、纤维蛋白降解产物 (Z=-4. 410,P <0. 001) 、D-二聚体 (Z=-4. 888,P <0. 001) 、中性粒细胞百分比 (Z=-3. 124,P=0. 002) 、门静脉主干内径 (t=2. 572,P=0. 012) 、门静脉血流速度 (t=-2. 441,P=0. 016) 、脾静脉内径 (t=3. 175,P=0... |
| Author | 顾宏图 吕靖 赵长青 董思思 刘成海 |
| AuthorAffiliation | 上海中医药大学附属曙光医院肝二科,上海,201203%上海中医药大学肝病研究所,上海,201203%上海中医药大学附属曙光医院肝二科,上海201203;上海中医药大学肝病研究所,上海201203 |
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| Copyright | 2019. This work is published under https://creativecommons.org/licenses/by-nc-nd/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. Copyright © Wanfang Data Co. Ltd. All Rights Reserved. |
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| Keywords | 证候 危险因素 肝硬化 门静脉血栓 |
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| Publisher | Journal of Clinical Hepatology 上海中医药大学附属曙光医院肝二科,上海,201203%上海中医药大学肝病研究所,上海,201203%上海中医药大学附属曙光医院肝二科,上海201203 上海中医药大学肝病研究所,上海201203 |
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| Snippet | 摘要:目的探讨肝硬化门静脉血栓 (PVT) 发生的危险因素及中医证候特点。方法选取2015年1月-2019年3月在上海中医药大学附属曙光医院住院的并发PVT的肝硬化患者62例,同时随机抽取66例无PVT肝硬化患者作为对照。收集并比较两组患者的临床资料。计量资料组间比较采用独立样本t检验或Mann-Whitney... R575.2; 目的 探讨肝硬化门静脉血栓(PVT)发生的危险因素及中医证候特点.方法... |
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| SubjectTerms | Flow velocity Liver cirrhosis Regression analysis Risk factors Spleen Thrombosis Traditional Chinese medicine Veins & arteries |
| Title | 肝硬化并发门静脉血栓的危险因素及中医证候特点 |
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