IL-35在HBV感染所致疾病中的调控作用和相关机制
IL-35主要是由调节性T淋巴细胞和调节性B淋巴细胞分泌的抑制性细胞因子，参与感染、肿瘤、自身免疫性疾病的发病。本文归纳了IL-35在HBV感染所致的乙型肝炎、肝硬化、肝衰竭和肝细胞癌中的免疫调节作用和机制。分析表明IL-35在HBV感染所致疾病中发挥双刃剑作用，促进感染慢性化和肝细胞癌疾病进展，也可降低肝脏炎症损伤，抑制肝纤维化。...
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| Published in | Linchuang gandanbing zazhi Vol. 38; no. 5; pp. 1148 - 1151 |
|---|---|
| Main Authors | , , |
| Format | Journal Article |
| Language | Chinese |
| Published |
Changchun
Journal of Clinical Hepatology
01.05.2022
空军军医大学第二附属医院(第四军医大学唐都医院)传染科,西安710038 |
| Subjects | |
| Online Access | Get full text |
| ISSN | 1001-5256 2097-3497 |
| DOI | 10.3969/j.issn.1001-5256.2022.05.036 |
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| Abstract | IL-35主要是由调节性T淋巴细胞和调节性B淋巴细胞分泌的抑制性细胞因子，参与感染、肿瘤、自身免疫性疾病的发病。本文归纳了IL-35在HBV感染所致的乙型肝炎、肝硬化、肝衰竭和肝细胞癌中的免疫调节作用和机制。分析表明IL-35在HBV感染所致疾病中发挥双刃剑作用，促进感染慢性化和肝细胞癌疾病进展，也可降低肝脏炎症损伤，抑制肝纤维化。 |
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| AbstractList | IL-35主要是由调节性T淋巴细胞和调节性B淋巴细胞分泌的抑制性细胞因子,参与感染、肿瘤、自身免疫性疾病的发病.本文归纳了IL-35在HBV感染所致的乙型肝炎、肝硬化、肝衰竭和肝细胞癌中的免疫调节作用和机制.分析表明IL-35在HBV感染所致疾病中发挥双刃剑作用,促进感染慢性化和肝细胞癌疾病进展,也可降低肝脏炎症损伤,抑制肝纤维化. IL-35主要是由调节性T淋巴细胞和调节性B淋巴细胞分泌的抑制性细胞因子，参与感染、肿瘤、自身免疫性疾病的发病。本文归纳了IL-35在HBV感染所致的乙型肝炎、肝硬化、肝衰竭和肝细胞癌中的免疫调节作用和机制。分析表明IL-35在HBV感染所致疾病中发挥双刃剑作用，促进感染慢性化和肝细胞癌疾病进展，也可降低肝脏炎症损伤，抑制肝纤维化。 |
| Author | 连建奇 杨晓飞 张野 |
| AuthorAffiliation | 空军军医大学第二附属医院(第四军医大学唐都医院)传染科,西安710038 |
| AuthorAffiliation_xml | – name: 空军军医大学第二附属医院(第四军医大学唐都医院)传染科,西安710038 |
| Author_FL | YANG Xiaofei ZHANG Ye LIAN Jianqi |
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| Keywords | 免疫调节 白细胞介素类 乙型肝炎病毒 |
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| Title | IL-35在HBV感染所致疾病中的调控作用和相关机制 |
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