肝硬化患者血常规与骨髓细胞学对比分析及脾切除术优选探讨
肝硬化分为代偿期和失代偿期，代偿期症状不典型，但失代偿期临床表现多样，其中大部分存在脾功能亢进，即脾肿大合并血常规异常 (白细胞、红细胞、血小板计数减少) 。在我国，脾切除的适应证包括继发性脾功能亢进、脾脏占位病变、外伤性脾破裂等，其中继发性脾功能亢进中最常见为肝硬化失代偿期。但经切除后有部分患者未见明显改善且面临一系列并发症。一直以来肝硬化失代偿期患者的血常规变化，主要是与脾功能亢进有关，但肝功能失代偿期引起的骨髓细胞学变化未予重视，更是容易忽视。正确诊断此类患者血常规变化的原因才是选择治疗方式的关键。因此，通过总结肝功能失代偿期患者血常规与其骨髓细胞学的关系变化，提示盲目切除脾脏的弊端，为...
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| Published in | Linchuang gandanbing zazhi Vol. 39; no. 9; pp. 2217 - 2224 |
|---|---|
| Main Authors | , , , , , |
| Format | Journal Article |
| Language | Chinese |
| Published |
Changchun
Journal of Clinical Hepatology
01.09.2023
西安交通大学第一临床医学院妇产科, 西安 710061%兰州大学第二临床医学院肝病科, 兰州 730000%兰州大学第二医院肝病科, 兰州 730000 |
| Subjects | |
| Online Access | Get full text |
| ISSN | 1001-5256 2097-3497 |
| DOI | 10.3969/j.issn.1001-5256.2023.09.028 |
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| Abstract | 肝硬化分为代偿期和失代偿期，代偿期症状不典型，但失代偿期临床表现多样，其中大部分存在脾功能亢进，即脾肿大合并血常规异常 (白细胞、红细胞、血小板计数减少) 。在我国，脾切除的适应证包括继发性脾功能亢进、脾脏占位病变、外伤性脾破裂等，其中继发性脾功能亢进中最常见为肝硬化失代偿期。但经切除后有部分患者未见明显改善且面临一系列并发症。一直以来肝硬化失代偿期患者的血常规变化，主要是与脾功能亢进有关，但肝功能失代偿期引起的骨髓细胞学变化未予重视，更是容易忽视。正确诊断此类患者血常规变化的原因才是选择治疗方式的关键。因此，通过总结肝功能失代偿期患者血常规与其骨髓细胞学的关系变化，提示盲目切除脾脏的弊端，为失代偿合并脾功能亢进患者的治疗方法提供正确认识和指导。 |
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| AbstractList | 肝硬化分为代偿期和失代偿期，代偿期症状不典型，但失代偿期临床表现多样，其中大部分存在脾功能亢进，即脾肿大合并血常规异常 (白细胞、红细胞、血小板计数减少) 。在我国，脾切除的适应证包括继发性脾功能亢进、脾脏占位病变、外伤性脾破裂等，其中继发性脾功能亢进中最常见为肝硬化失代偿期。但经切除后有部分患者未见明显改善且面临一系列并发症。一直以来肝硬化失代偿期患者的血常规变化，主要是与脾功能亢进有关，但肝功能失代偿期引起的骨髓细胞学变化未予重视，更是容易忽视。正确诊断此类患者血常规变化的原因才是选择治疗方式的关键。因此，通过总结肝功能失代偿期患者血常规与其骨髓细胞学的关系变化，提示盲目切除脾脏的弊端，为失代偿合并脾功能亢进患者的治疗方法提供正确认识和指导。 肝硬化分为代偿期和失代偿期,代偿期症状不典型,但失代偿期临床表现多样,其中大部分存在脾功能亢进,即脾肿大合并血常规异常(白细胞、红细胞、血小板计数减少).在我国,脾切除的适应证包括继发性脾功能亢进、脾脏占位病变、外伤性脾破裂等,其中继发性脾功能亢进中最常见为肝硬化失代偿期.但经切除后有部分患者未见明显改善且面临一系列并发症.一直以来肝硬化失代偿期患者的血常规变化,主要是与脾功能亢进有关,但肝功能失代偿期引起的骨髓细胞学变化未予重视,更是容易忽视.正确诊断此类患者血常规变化的原因才是选择治疗方式的关键.因此,通过总结肝功能失代偿期患者血常规与其骨髓细胞学的关系变化,提示盲目切除脾脏的弊端,为失代偿合并脾功能亢进患者的治疗方法提供正确认识和指导. |
| Author | 黄飞 李惠敏 黄霄 赵睿 陈艺卓 李欢欢 |
| AuthorAffiliation | 西安交通大学第一临床医学院妇产科, 西安 710061%兰州大学第二临床医学院肝病科, 兰州 730000%兰州大学第二医院肝病科, 兰州 730000 |
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| Author_FL | LI Huanhuan LI Huimin ZHAO Rui HUANG Xiao CHEN Yizhuo HUANG Fei |
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| Keywords | Splenectomy 脾切除术 脾功能亢进 Liver Cirrhosis 肝硬化 Hypersplenism |
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| Title | 肝硬化患者血常规与骨髓细胞学对比分析及脾切除术优选探讨 |
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