早期经颈静脉肝内门体分流术临床应用及研究进展
经颈静脉肝内门体分流术(TIPS)是经颈静脉途径在肝静脉与门静脉之间穿刺建立门体分流通道以此来降低门静脉压力，从而控制急性食管胃静脉曲张出血(EGVB)。EGVB的预后在过去几十年有了显著的改善，目前内镜下套扎联合药物治疗被推荐为一线治疗方案。过去十年EGVB管理的最新进展和研究聚焦在相对较新的“early”或“pre-emptive”TIPS概念，即在标准治疗失败风险较高的EGVB患者中，推荐早期TIPS(入院72 h内，理想情况下24 h内)治疗。本文简要介绍早期TIPS对控制出血、病死率以及肝性脑病的影响，早期TIPS适用的高危人群、干预的时机及成本效益，早期TIPS在真实世界中的应用以...
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| Published in | Linchuang gandanbing zazhi Vol. 39; no. 7; pp. 1513 - 1522 |
|---|---|
| Main Authors | , , , , |
| Format | Journal Article |
| Language | Chinese |
| Published |
Changchun
Journal of Clinical Hepatology
01.07.2023
苏州大学附属第一医院介入科, 江苏苏州215000 |
| Subjects | |
| Online Access | Get full text |
| ISSN | 1001-5256 2097-3497 |
| DOI | 10.3969/j.issn.1001-5256.2023.07.001 |
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| Abstract | 经颈静脉肝内门体分流术(TIPS)是经颈静脉途径在肝静脉与门静脉之间穿刺建立门体分流通道以此来降低门静脉压力，从而控制急性食管胃静脉曲张出血(EGVB)。EGVB的预后在过去几十年有了显著的改善，目前内镜下套扎联合药物治疗被推荐为一线治疗方案。过去十年EGVB管理的最新进展和研究聚焦在相对较新的“early”或“pre-emptive”TIPS概念，即在标准治疗失败风险较高的EGVB患者中，推荐早期TIPS(入院72 h内，理想情况下24 h内)治疗。本文简要介绍早期TIPS对控制出血、病死率以及肝性脑病的影响，早期TIPS适用的高危人群、干预的时机及成本效益，早期TIPS在真实世界中的应用以及国际指南和共识对早期TIPS的推荐。 |
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| AbstractList | 经颈静脉肝内门体分流术(TIPS)是经颈静脉途径在肝静脉与门静脉之间穿刺建立门体分流通道以此来降低门静脉压力,从而控制急性食管胃静脉曲张出血(EGVB).EGVB的预后在过去几十年有了显著的改善,目前内镜下套扎联合药物治疗被推荐为一线治疗方案.过去十年EGVB管理的最新进展和研究聚焦在相对较新的"early"或"pre-emptive"TIPS概念,即在标准治疗失败风险较高的EGVB患者中,推荐早期TIPS(入院72h内,理想情况下24h内)治疗.本文简要介绍早期TIPS对控制出血、病死率以及肝性脑病的影响,早期TIPS适用的高危人群、干预的时机及成本效益,早期TIPS在真实世界中的应用以及国际指南和共识对早期TIPS的推荐. 经颈静脉肝内门体分流术(TIPS)是经颈静脉途径在肝静脉与门静脉之间穿刺建立门体分流通道以此来降低门静脉压力，从而控制急性食管胃静脉曲张出血(EGVB)。EGVB的预后在过去几十年有了显著的改善，目前内镜下套扎联合药物治疗被推荐为一线治疗方案。过去十年EGVB管理的最新进展和研究聚焦在相对较新的“early”或“pre-emptive”TIPS概念，即在标准治疗失败风险较高的EGVB患者中，推荐早期TIPS(入院72 h内，理想情况下24 h内)治疗。本文简要介绍早期TIPS对控制出血、病死率以及肝性脑病的影响，早期TIPS适用的高危人群、干预的时机及成本效益，早期TIPS在真实世界中的应用以及国际指南和共识对早期TIPS的推荐。 |
| Author | 沈健 黄金涛 王泽 朱晓黎 仲斌演 |
| AuthorAffiliation | 苏州大学附属第一医院介入科, 江苏苏州215000 |
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| Author_FL | ZHU Xiaoli HUANG Jintao SHEN Jian ZHONG Binyan WANG Ze |
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| Keywords | Esophageal and Gastric Varices Portasystemic Shunt,Transjugular Intrahepatic 门体分流术,经颈静脉肝内 出血 食管和胃静脉曲张 Hemorrhage |
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| Title | 早期经颈静脉肝内门体分流术临床应用及研究进展 |
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