肺炎克雷伯菌肝脓肿与大肠埃希菌肝脓肿临床特点对比分析

摘要:目的肺炎克雷伯菌肝脓肿 (KPLA) 与大肠埃希菌肝脓肿 (ECLA) 为临床上最常见的两种细菌性肝脓肿,分析这两种肝脓肿的临床特征,为早期诊断及有效治疗提供参考。方法回顾性分析2005年3月-2018年7月空军军医大学第二附属医院收治的371例肝脓肿患者资料,其中病原学检查阳性145例。比较KPLA与ECLA患者的临床特点、实验室检查、影像学检查及预后。计量资料两组间比较采用t检验或Mann-Whitney U检验。计数资料两组间比较采用χ2检验或Fisher精确检验。采用多因素logistic回归分析预后的影响因素。结果 145例病原学检查阳性患者中,肺炎克雷伯菌培养阳性66例,大肠...

Full description

Saved in:
Bibliographic Details
Published inLinchuang gandanbing zazhi Vol. 36; no. 9; pp. 2010 - 2014
Main Authors 姚娜, 康文, 连建奇, 王临旭, 张谷芬, 王素娜, 汪春付
Format Journal Article
LanguageChinese
Published Changchun Journal of Clinical Hepatology 01.09.2020
空军军医大学第二附属医院(唐都医院)传染科,西安710038
Subjects
Abscesses
Antibiotics
E coli
Gallbladder diseases
Liver
Multidrug resistant organisms
Pathogens
Regression analysis
疾病特征
大肠杆菌
肝脓肿
肺炎克雷伯菌
Online AccessGet full text
ISSN1001-5256
2097-3497
DOI10.3969/j.issn.1001-5256.2020.09.020

Cover

Abstract 摘要:目的肺炎克雷伯菌肝脓肿 (KPLA) 与大肠埃希菌肝脓肿 (ECLA) 为临床上最常见的两种细菌性肝脓肿,分析这两种肝脓肿的临床特征,为早期诊断及有效治疗提供参考。方法回顾性分析2005年3月-2018年7月空军军医大学第二附属医院收治的371例肝脓肿患者资料,其中病原学检查阳性145例。比较KPLA与ECLA患者的临床特点、实验室检查、影像学检查及预后。计量资料两组间比较采用t检验或Mann-Whitney U检验。计数资料两组间比较采用χ2检验或Fisher精确检验。采用多因素logistic回归分析预后的影响因素。结果 145例病原学检查阳性患者中,肺炎克雷伯菌培养阳性66例,大肠埃希菌培养阳性42例。与KPLA患者相比,ECLA更好发于年龄较大人群 (t=-2.250,P=0.027) ,多合并胆道疾病 (χ2=10.019,P=0.002) 、腹部手术史 (χ2=27.481,P <0.001) 、肿瘤 (χ2=17.745,P <0.001) ,多出现复发性肝脓肿 (χ2=13.745,P <0.001) 。KPLA好发于糖尿病患者 (χ2=17.505,P <0.001) 。实验...
AbstractList R575.4; 目的 肺炎克雷伯菌肝脓肿(KPLA)与大肠埃希菌肝脓肿(ECLA)为临床上最常见的两种细菌性肝脓肿,分析这两种肝脓肿的临床特征,为早期诊断及有效治疗提供参考.方法 回顾性分析2005年3月-2018年7月空军军医大学第二附属医院收治的371例肝脓肿患者资料,其中病原学检查阳性145例.比较KPLA与ECLA患者的临床特点、实验室检查、影像学检查及预后.计量资料两组间比较采用t检验或Mann-Whitney U检验.计数资料两组间比较采用χ2检验或Fisher精确检验.采用多因素lo-gistic回归分析预后的影响因素.结果 145例病原学检查阳性患者中,肺炎克雷伯菌培养阳性66例,大肠埃希菌培养阳性42例.与KPLA患者相比,ECLA更好发于年龄较大人群(t=-2.250,P=0.027),多合并胆道疾病(χ2=10.019,P=0.002)、腹部手术史(χ2=27.481,P<0.001)、肿瘤(χ2=17.745,P<0.001),多出现复发性肝脓肿(χ2=13.745,P<0.001).KPLA好发于糖尿病患者(χ2=17.505,P<0.001).实验室检查方面,与KPLA患者相比,ECLA患者TBil水平较高(U=880.000,P=0.001),Alb(t=-2.625,P=0.010)、PLT(U=1719.000,P=0.036)水平降低.影像学分析显示,ECLA常见多发肝脓肿(χ2=23.372,P<0.001),KPLA脓肿直径多大于5 cm(χ2=7.637,P=0.006).并发症方面,ECLA更易出现肺部感染(χ2=18.857,P<0.001)和肺气肿(P=0.013).ECLA易出现多重耐药菌,两组在治疗方面均多采用抗生素联合B超引导下穿刺引流.多因素logistic回归分析显示预后的影响因素为患者入院APACHEⅡ评分(比值比=0.049,95％可信区间:0.026～0.266,P<0.001).结论 ECLA多发生于年龄较大且合并胆道疾病患者,易复发,影像学常见多发性脓肿,易合并肺炎及肺气肿,ECLA产超广谱β-内酰胺酶阳性率较高,需早期合理应用抗生素.
摘要:目的肺炎克雷伯菌肝脓肿 (KPLA) 与大肠埃希菌肝脓肿 (ECLA) 为临床上最常见的两种细菌性肝脓肿,分析这两种肝脓肿的临床特征,为早期诊断及有效治疗提供参考。方法回顾性分析2005年3月-2018年7月空军军医大学第二附属医院收治的371例肝脓肿患者资料,其中病原学检查阳性145例。比较KPLA与ECLA患者的临床特点、实验室检查、影像学检查及预后。计量资料两组间比较采用t检验或Mann-Whitney U检验。计数资料两组间比较采用χ2检验或Fisher精确检验。采用多因素logistic回归分析预后的影响因素。结果 145例病原学检查阳性患者中,肺炎克雷伯菌培养阳性66例,大肠埃希菌培养阳性42例。与KPLA患者相比,ECLA更好发于年龄较大人群 (t=-2.250,P=0.027) ,多合并胆道疾病 (χ2=10.019,P=0.002) 、腹部手术史 (χ2=27.481,P <0.001) 、肿瘤 (χ2=17.745,P <0.001) ,多出现复发性肝脓肿 (χ2=13.745,P <0.001) 。KPLA好发于糖尿病患者 (χ2=17.505,P <0.001) 。实验...
Author 张谷芬
王素娜
姚娜
康文
连建奇
汪春付
王临旭
AuthorAffiliation 空军军医大学第二附属医院(唐都医院)传染科,西安710038
AuthorAffiliation_xml – name: 空军军医大学第二附属医院(唐都医院)传染科,西安710038
Author_FL KANG Wen
ZHANG Gufen
WANG Chunfu
WANG Suna
WANG Linxu
YAO Na
LIAN Jianqi
Author_FL_xml – sequence: 1
  fullname: YAO Na
– sequence: 2
  fullname: KANG Wen
– sequence: 3
  fullname: LIAN Jianqi
– sequence: 4
  fullname: WANG Linxu
– sequence: 5
  fullname: ZHANG Gufen
– sequence: 6
  fullname: WANG Suna
– sequence: 7
  fullname: WANG Chunfu
Author_xml – sequence: 1
  fullname: 姚娜
– sequence: 2
  fullname: 康文
– sequence: 3
  fullname: 连建奇
– sequence: 4
  fullname: 王临旭
– sequence: 5
  fullname: 张谷芬
– sequence: 6
  fullname: 王素娜
– sequence: 7
  fullname: 汪春付
BookMark eNpVkMtKw0AYhQdRsNY-hS7cJP4z_yRxllK8QdGNrsskmZSWktbGInQZL3gpVdCdeFkILrsRbIvgy3Ta-BZGKoqbcxbn4xw4c2Q6rIWKkEUKJgpbLFfMchSFJgWghsUs22TAwARhpjZFMgyEYyAXzjTJ_DKzJBdFZRcsirbglp0h20k8GMcdfXL5efc2fO8mV-0kvk-Ob5L4Y9jr6OeXJH7Sj0e61_4fverBxfi8P477utsfdW_12eno4XqezASyGqncj2fJ3vrabn7TKOxsbOVXC0adIgVDyUAJx7FX0PMlOC6Ax8HlKCVjjseoQOZb0ncAEZArmyrOfcYCidQHZXmYJUuT3kMZBjIsFSu1ZiNMF4tVr-S7rdb3GSBSSdGFCVpv1PabKjr4Y5FxoCiYYPgFuXh9Kg
ClassificationCodes R575.4
ContentType Journal Article
Copyright 2020. This work is published under https://creativecommons.org/licenses/by-nc-nd/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.
Copyright © Wanfang Data Co. Ltd. All Rights Reserved.
Copyright_xml – notice: 2020. This work is published under https://creativecommons.org/licenses/by-nc-nd/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.
– notice: Copyright © Wanfang Data Co. Ltd. All Rights Reserved.
DBID 3V.
7X7
7XB
88E
8FI
8FJ
8FK
ABUWG
AFKRA
AZQEC
BENPR
CCPQU
DWQXO
FYUFA
GHDGH
K9.
M0S
M1P
PHGZM
PHGZT
PIMPY
PJZUB
PKEHL
PPXIY
PQEST
PQQKQ
PQUKI
2B.
4A8
92I
93N
PSX
TCJ
DOI 10.3969/j.issn.1001-5256.2020.09.020
DatabaseName ProQuest Central (Corporate)
Health & Medical Collection
ProQuest Central (purchase pre-March 2016)
Medical Database (Alumni Edition)
Hospital Premium Collection
Hospital Premium Collection (Alumni Edition)
ProQuest Central (Alumni) (purchase pre-March 2016)
ProQuest Central (Alumni Edition)
ProQuest Central UK/Ireland
ProQuest Central Essentials
ProQuest Central
ProQuest One Community College
ProQuest Central Korea
Health Research Premium Collection
Health Research Premium Collection (Alumni)
ProQuest Health & Medical Complete (Alumni)
Health & Medical Collection (Alumni Edition)
Medical Database
ProQuest Central Premium
ProQuest One Academic (New)
Publicly Available Content Database
ProQuest Health & Medical Research Collection
ProQuest One Academic Middle East (New)
ProQuest One Health & Nursing
ProQuest One Academic Eastern Edition (DO NOT USE)
ProQuest One Academic
ProQuest One Academic UKI Edition
Wanfang Data Journals - Hong Kong
WANFANG Data Centre
Wanfang Data Journals
万方数据期刊 - 香港版
China Online Journals (COJ)
China Online Journals (COJ)
DatabaseTitle Publicly Available Content Database
ProQuest One Academic Middle East (New)
ProQuest Central Essentials
ProQuest Health & Medical Complete (Alumni)
ProQuest Central (Alumni Edition)
ProQuest One Community College
ProQuest One Health & Nursing
ProQuest Central
ProQuest Health & Medical Research Collection
Health Research Premium Collection
Health and Medicine Complete (Alumni Edition)
ProQuest Central Korea
Health & Medical Research Collection
ProQuest Central (New)
ProQuest Medical Library (Alumni)
ProQuest One Academic Eastern Edition
ProQuest Hospital Collection
Health Research Premium Collection (Alumni)
ProQuest Hospital Collection (Alumni)
ProQuest Health & Medical Complete
ProQuest Medical Library
ProQuest One Academic UKI Edition
ProQuest One Academic
ProQuest One Academic (New)
ProQuest Central (Alumni)
DatabaseTitleList
Publicly Available Content Database
Database_xml – sequence: 1
  dbid: BENPR
  name: ProQuest Central
  url: https://www.proquest.com/central
  sourceTypes: Aggregation Database
DeliveryMethod fulltext_linktorsrc
Discipline Medicine
DocumentTitle_FL Clinical features of Klebsiella pneumoniae liver abscess versus Escherichia coli liver abscess
EISSN 2097-3497
EndPage 2014
ExternalDocumentID lcgdbzz202009020
GrantInformation_xml – fundername: 国家科技重大专项
  funderid: (2017ZX10204401-002-005)
GroupedDBID -05
3V.
5XA
5XF
7X7
7XB
88E
8FI
8FJ
8FK
92F
92I
ABDBF
ABJNI
ABUWG
ACGFS
ACUHS
AFKRA
ALMA_UNASSIGNED_HOLDINGS
AZQEC
BENPR
CCEZO
CCPQU
CIEJG
CW9
DWQXO
EAD
EAP
EOJEC
ESX
FYUFA
K9.
M1P
OBODZ
OK1
PHGZM
PHGZT
PIMPY
PJZUB
PKEHL
PPXIY
PQEST
PQQKQ
PQUKI
RNS
TCJ
TGQ
U1G
U5O
2B.
4A8
93N
IPNFZ
PSX
RIG
ID FETCH-LOGICAL-p1310-eafe977683cda07b00c40b43aa227c21932d5ad7033034e61e44d22fa31d0e5c3
IEDL.DBID 7X7
ISSN 1001-5256
IngestDate Thu May 29 04:06:09 EDT 2025
Sat Aug 23 13:09:01 EDT 2025
IsDoiOpenAccess true
IsOpenAccess true
IsPeerReviewed true
IsScholarly true
Issue 9
Keywords 疾病特征
大肠杆菌
肝脓肿
肺炎克雷伯菌
Language Chinese
LinkModel DirectLink
MergedId FETCHMERGED-LOGICAL-p1310-eafe977683cda07b00c40b43aa227c21932d5ad7033034e61e44d22fa31d0e5c3
Notes ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 14
OpenAccessLink https://www.proquest.com/docview/3240139292?pq-origsite=%requestingapplication%
PQID 3240139292
PQPubID 7350069
PageCount 5
ParticipantIDs wanfang_journals_lcgdbzz202009020
proquest_journals_3240139292
PublicationCentury 2000
PublicationDate 2020-09-01
PublicationDateYYYYMMDD 2020-09-01
PublicationDate_xml – month: 09
  year: 2020
  text: 2020-09-01
  day: 01
PublicationDecade 2020
PublicationPlace Changchun
PublicationPlace_xml – name: Changchun
PublicationTitle Linchuang gandanbing zazhi
PublicationTitle_FL Journal of Clinical Hepatology
PublicationYear 2020
Publisher Journal of Clinical Hepatology
空军军医大学第二附属医院(唐都医院)传染科,西安710038
Publisher_xml – name: Journal of Clinical Hepatology
– name: 空军军医大学第二附属医院(唐都医院)传染科,西安710038
SSID ssib051369456
ssib061082477
ssj0041983
ssib001103858
ssib053243598
ssib002264326
ssib038074677
Score 2.2260852
Snippet 摘要:目的肺炎克雷伯菌肝脓肿 (KPLA) 与大肠埃希菌肝脓肿 (ECLA)...
R575.4; 目的 肺炎克雷伯菌肝脓肿(KPLA)与大肠埃希菌肝脓肿(ECLA)为临床上最常见的两种细菌性肝脓肿,分析这两种肝脓肿的临床特征,为早期诊断及有效治疗提供参考.方法...
SourceID wanfang
proquest
SourceType Aggregation Database
StartPage 2010
SubjectTerms Abscesses
Antibiotics
E coli
Gallbladder diseases
Liver
Multidrug resistant organisms
Pathogens
Regression analysis
Title 肺炎克雷伯菌肝脓肿与大肠埃希菌肝脓肿临床特点对比分析
URI https://www.proquest.com/docview/3240139292
https://d.wanfangdata.com.cn/periodical/lcgdbzz202009020
Volume 36
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV1LS8NAEF58oHgRn_hGwWs0u9kk5iRWLSJYRBR6k93sVhFpfSL0GB_4QgW9iY-D4LEXQSuCf8bY-C-cTVPbXjyFMHnA7O7MN7Oz3yA0LInFdVPYmsCOq1EOY8EtzjUX_AlXLd1lmMqeS1gzS3Q2aSajhNt2VFZZsomhoRYZV-XIRxVxHFbOnIxvbGqqa5TaXY1aaNSiekVdpkq67GTZnWKsV3G1qEOjFXBFca3TCjo3ExuWQ8vcMib8UxHcle4BaYyR8Nxm0dJTCNiLBfwQkpuAHRrRsIqCHcsZXQvX8MifCCJRooeMqkSvArMNeyydYumVCq8Wb0HNERwdnCjOn1ZUk11tQ41z0YZ7O0oE3nvBu_APz35uX78-csHleeDdBQfXgff59XbhPz0H3qP_sO-_nVeLXvz308JJvuDl_Vz-O3fjHx993191oKX49OLkjBa1YNA2MAA_TbKUBIRojRmuYLoNOnSpzqnBGCG2SxT6EyYTYDbAFVJpYUmpICTFDCx0abpGJ6pLZ9KyCw0Ki8K7gIgYT4HnNBhE5qakmHABINCxu1FfSSvL0TraXi6PejcaijRVlq67K4Jns0q1qrxU7_n_E72oST1arBDrQ3U7W7uyHyDFDh8I580Aqp-ITcXicI1NJ-YXfgEzXdoN
linkProvider ProQuest
linkToHtml http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwY2BQSTUySzIwTTHXTTG0TNY1SQLGRZJZUpJuMrA-SQJd6Z4KHsr29TPzCDXxijCNYGJYB9sLA1pWCSsTwQV1Sn4yaIxcH3RwnCGoMjeyLyjUBd0aBZpdhV2hAUkW3qmV5cAuW7GtpwswflWNjNxcQ5w9dKG3CugWGALbMrqpiWmpwEaPmYVxckqigTkw2SWbGCSZGCcmGhmZJxuBGjQppokpwJwALN1NUs0MU01MUoyM0hKNDVMMUk2TjYHmMjOwmhgDuzIsDKxOrn4BQYgGiKEByukwoG2qSA0k0OnuJkgHyJkaGptZmiBOszEF-hJ0pB6MD2zbWBiBd4pC6hYTQ0sLyJYBA0NgF9LUjINBBdTvtjSz1M8Clxp6cClg39fIAHyGq5EBSvOZvTwxLy0xLx2pHnUTZOCHNoAVHCEpVoiBqSpDmIHDFzrFL8Lg96Jp1_Omvqet3S9nb3-yZ_2L_p4XTXNftEx-0bT_yY6-p0uWv2ha8HR-89MdPahSW57u6nreufN5086n63c-Wz_laUfbs3kTRBlCaRI9Ygwsefl5qRIMCilmJkC9wDZYYlIasK42TjQwMTNNNTE0SkoBNjstzSUZZGChEg_NucXxiHQmyaAIDSmEbE5yekpSVRUoaEELWg2k8Bshz8DpEeLrE-_j6ectzcAF0gZZnybDwFJSVJoqC2zQlCTJQVORAkMCrRMuAL8-FEM
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=%E8%82%BA%E7%82%8E%E5%85%8B%E9%9B%B7%E4%BC%AF%E8%8F%8C%E8%82%9D%E8%84%93%E8%82%BF%E4%B8%8E%E5%A4%A7%E8%82%A0%E5%9F%83%E5%B8%8C%E8%8F%8C%E8%82%9D%E8%84%93%E8%82%BF%E4%B8%B4%E5%BA%8A%E7%89%B9%E7%82%B9%E5%AF%B9%E6%AF%94%E5%88%86%E6%9E%90&rft.jtitle=%E4%B8%B4%E5%BA%8A%E8%82%9D%E8%83%86%E7%97%85%E6%9D%82%E5%BF%97&rft.au=%E5%A7%9A%E5%A8%9C&rft.au=%E5%BA%B7%E6%96%87&rft.au=%E8%BF%9E%E5%BB%BA%E5%A5%87&rft.au=%E7%8E%8B%E4%B8%B4%E6%97%AD&rft.date=2020-09-01&rft.pub=%E7%A9%BA%E5%86%9B%E5%86%9B%E5%8C%BB%E5%A4%A7%E5%AD%A6%E7%AC%AC%E4%BA%8C%E9%99%84%E5%B1%9E%E5%8C%BB%E9%99%A2%28%E5%94%90%E9%83%BD%E5%8C%BB%E9%99%A2%29%E4%BC%A0%E6%9F%93%E7%A7%91%2C%E8%A5%BF%E5%AE%89710038&rft.issn=1001-5256&rft.volume=36&rft.issue=9&rft.spage=2010&rft.epage=2014&rft_id=info:doi/10.3969%2Fj.issn.1001-5256.2020.09.020&rft.externalDocID=lcgdbzz202009020
thumbnail_s http://utb.summon.serialssolutions.com/2.0.0/image/custom?url=http%3A%2F%2Fwww.wanfangdata.com.cn%2Fimages%2FPeriodicalImages%2Flcgdbzz%2Flcgdbzz.jpg