Interactions and collider bias in case-only gene-environment data

Background: Case-only design for gene-environment interaction (CODGEI) relies on the rare disease assumption. A negative association due to collider bias appears between gene and environment when this assumption is not respected. Genetic risk estimation can quantify part of the predisposition of an...

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Bibliographic Details
Published inbioRxiv
Main Authors F lix Balazard, Sophie Le Fur, Pierre Bougn res, Alain-Jacques Valleron, The Isis-Diab Collaborative Group
Format Paper
LanguageEnglish
Published Cold Spring Harbor Cold Spring Harbor Laboratory Press 20.09.2017
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