Design of protein homocystamides with enhanced tumor uptake properties for (19)F magnetic resonance imaging - Chubarov, Alexey S; Zakharova, Olga D; Koval, Olga A; Romaschenko, Alexander V; Akulov, Andrey E; Zavjalov, Evgenii L; Razumov, Ivan A; Koptyug, Igor V; Knorre, Dmitry G; Godovikova, Tatyana S (Bioorganic & medicinal chemistry, 2015)
Keywords: Animals; Brain - metabolism; Cell Line, Tumor; Cell Survival - drug effects; Contrast Media - chemistry; Contrast Media - metabolism; Contrast Media - toxicity; Drug Design; Female; Fluorine-19 Magnetic Resonance Imaging; Free Radicals - metabolism; Homocysteine - analogs & derivatives; Homocysteine - chemistry; Homocysteine - metabolism; Humans; Mice; Mice, SCID; Microscopy, Fluorescence; Neoplasms - diagnosis; Neoplasms - diagnostic imaging; Radiography; Serum Albumin - chemistry; Serum Albumin - metabolism; Transplantation, Heterologous; Human serum albumin; Perfluorotoluene; Protein aggregation; Thiyl radical; N-homocysteinylation; Dual-labeled albumin-based molecular probe; Homocysteine thiolactone; Fluorine magnetic resonance imaging; Fluorinated homocysteine thiolactone; Glioma model