Serum of transthyretin as a treatment-responsive biomarker for schizophrenia

• Published in: Brain and nerve = Shinkei kenkyū no shinpo Vol. 65; no. 9; p. 1093
• Main Authors: Nakagawa, Nobuaki, Yao, Hiroshi, Nakahara, Tatsuo, Inomata, Shinsaku, Hashimoto, Kijiro, Kuroki, Toshihide
• Format: Journal Article
• Language: Japanese
• Published: Japan 01.09.2013
• Subjects: Adult; Biomarkers - blood; Enzyme-Linked Immunosorbent Assay - methods; Female; Humans; Male; Mass Spectrometry - methods; Peptide Mapping - methods; Prealbumin - analysis; Prealbumin - metabolism; Proteomics - methods; Schizophrenia - blood; Schizophrenia - drug therapy; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization - methods; Young Adult

We investigated the changes in protein profiles of treatment responsive biomarkers in three subjects with first-onset schizophrenia using the surface enhanced laser desorption/ionization time-of-flight mass spectrometry (SELDI-TOF-MS) technology. Our results showed that eight protein peaks were down...