Current insights into chromatin structure organization

This review summarizes current insights into organization of chromatin structure at different levels of DNA compaction. Analysis of available experimental data allowed concluding that only nucleosomal level of structural organization was sufficiently investigated, whereas structure of a 30-nm chroma...

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Bibliographic Details
Published inT͡S︡itologii͡a Vol. 54; no. 4; p. 298
Main Authors Ilatovskiĭ, A V, Lebedev, D V, Filatov, M V, Petukhov, M G, Isaev-Ivanov, V V
Format Journal Article
LanguageRussian
Published Russia (Federation) 2012
Subjects
Cell Nucleus - chemistry
Cell Nucleus - ultrastructure
Chromatin - chemistry
Chromatin - ultrastructure
DNA - chemistry
DNA - ultrastructure
Fractals
Histones - chemistry
Histones - ultrastructure
Nucleic Acid Conformation
Nucleosomes - chemistry
Nucleosomes - ultrastructure
Protein Conformation
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Summary:This review summarizes current insights into organization of chromatin structure at different levels of DNA compaction. Analysis of available experimental data allowed concluding that only nucleosomal level of structural organization was sufficiently investigated, whereas structure of a 30-nm chromatin fiber remains an open issue. The data on the chromatin structure obtained at the level of the nucleus speak in favor of a biphasic fractal organization of chromatin.
ISSN:0041-3771