Incidence of complication and tumor recurrence after radiofrequency ablation in high-risk location of hepatocellular carcinoma patients

To evaluate complication, rate of residual, and tumor recurrence in high-risk location compared to non-high-risk location in hepatocellular carcinoma patients. Radiofrequency ablation was performed on 409 tumors in Siriraj Hospital between October 2009 and May 2012. Eighty-eight nodules in 78 atient...

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Published inJournal of the Medical Association of Thailand Vol. 97; no. 1; p. 95
Main Authors Thamtorawat, Somrach, Limsuwarn, Panida, Tongdee, Trongtum, Chaiyasoot, Walailak, Siriapisith, Thanongchai
Format Journal Article
LanguageEnglish
Published Thailand 01.01.2014
Subjects
Adult
Aged
Aged, 80 and over
Carcinoma, Hepatocellular - surgery
Catheter Ablation - adverse effects
Female
Humans
Liver Neoplasms - surgery
Male
Middle Aged
Neoplasm Recurrence, Local
Neoplasm, Residual
Retrospective Studies
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Summary:To evaluate complication, rate of residual, and tumor recurrence in high-risk location compared to non-high-risk location in hepatocellular carcinoma patients. Radiofrequency ablation was performed on 409 tumors in Siriraj Hospital between October 2009 and May 2012. Eighty-eight nodules in 78 atients were treated by RF ablation, which divided into high risk and non-high-risk location. Complete ablation rate, residual tumor recurrent tumor, and complication were retrospectively reviewed. HCC nodules were in non-high-risk location 34 nodules (38.6%) and in high-risk location 54 nodules (61.4%). Complete tumor ablations were done in 34 nodules (100%) of non-high-risk location group and 50 nodules (92.6%) of high-risk location group. All residual tumors were four nodules (7.2%), which located in subcapsular location. Recurrent tumors were found in six nodules (6.8%), and mean time to recurrence were 210.2 days. Early complication was 10.2% and late complication was 4.5%. The recurrent tumor and complication were not significantly different between two groups. Radiofrequency ablation is effective treatment of hepatocellular carcinoma in high-risk location tumor There is no significant difference in complication and tumor recurrent rate between high-risk and non-high-risk group. However incidence of residual tumor is significantly increased in subcapsular location tumor
ISSN:0125-2208