Study on the association between genetic variation of gag gene and HLA restricted CTL response in HIV-1 B' infected Chinese people

• Published in: Zhong hua yi xue za zhi Vol. 93; no. 7; p. 541
• Main Authors: Zhang, Hui, Han, Xiao-xu, Dai, Di, Zhao, Bin, An, Ming-hui, Shang, Hong
• Format: Journal Article
• Language: Chinese
• Published: China 19.02.2013
• Subjects: Asian Continental Ancestry Group - genetics; China; Epitopes, T-Lymphocyte - immunology; gag Gene Products, Human Immunodeficiency Virus - genetics; gag Gene Products, Human Immunodeficiency Virus - immunology; Genetic Variation; HIV Seropositivity; Humans; T-Lymphocytes, Cytotoxic - immunology; China

To identify the genetic variation of Gag gene in HIV-1 B' subtype infected Chinese people and to evaluate the association between the positive selection sites and HLA restricted CTL response. We downloaded all HIV-1 B' subtype gag gene sampled from China from the LANL HIV database. The seq...