(123)I-MIBG Scintigraphy in the Subacute State of Takotsubo Cardiomyopathy

• Published in: JACC. Cardiovascular imaging Vol. 9; no. 8; pp. 982 - 990
• Main Authors: Christensen, Thomas Emil, Bang, Lia Evi, Holmvang, Lene, Skovgaard, Dorthe Charlotte, Oturai, Ditte Bang, Søholm, Helle, Thomsen, Jakob Hartvig, Andersson, Hedvig Bille, Ghotbi, Adam Ali, Ihlemann, Nikolaj, Kjaer, Andreas, Hasbak, Philip
• Format: Journal Article
• Language: English
• Published: United States 01.08.2016
• Subjects: 3-Iodobenzylguanidine - administration & dosage; Aged; Biomarkers - blood; Case-Control Studies; Echocardiography; Epinephrine - blood; Female; Heart - diagnostic imaging; Heart - innervation; Humans; Male; Middle Aged; Norepinephrine - blood; Predictive Value of Tests; Prospective Studies; Radiopharmaceuticals - administration & dosage; Stroke Volume; Sympathetic Nervous System - metabolism; Sympathetic Nervous System - physiopathology; Takotsubo Cardiomyopathy - blood; Takotsubo Cardiomyopathy - diagnostic imaging; Takotsubo Cardiomyopathy - physiopathology; Ventricular Function, Left; heart failure; iodine-123–meta-iodobenzylguanidine scintigraphy; takotsubo cardiomyopathy; plasma catecholamines

The study sought to investigate adrenergic activity in patients with takotsubo cardiomyopathy (TTC). TTC is a specific type of reversible heart failure possibly caused by excessive catecholamine stimulation of the myocardium. Scintigraphic iodine-123-meta-iodobenzylguanidine (mIBG) imaging of the he...