Development and evaluation of individualized fluid therapy in the elderly patients with coronary heart disease undergoing gastrointestinal surgery: a randomized, controlled trial

• Published in: Zhonghua wei chang wai ke za zhi Vol. 15; no. 6; p. 564
• Main Authors: Zheng, Hong, Guo, Hai, Ye, Jian-rong, Chen, Lin
• Format: Journal Article
• Language: Chinese
• Published: China 01.06.2012
• Subjects: Aged; Aged, 80 and over; Coronary Disease; Digestive System Surgical Procedures; Female; Fluid Therapy - methods; Humans; Male; Middle Aged; Monitoring, Intraoperative; Perioperative Care; Prospective Studies
• ISSN: 1671-0274

To develop and evaluate an individualized fluid therapy in the elderly patients with coronary heart disease undergoing gastrointestinal surgery. In this prospective study, 60 coronary heart disease patients undergoing gastrointestinal surgery were included in the First Affiliated Hospital of Xinjiang Medical University from March 2009 to March 2012. Patients were randomized into the intervention group and the control group with 30 patients in each group. Individualized fluid therapy was used during surgery and postoperative period in the ICU, which was determined based on target controlled fluid therapy according to cardiac index, stroke volume, and stroke volume variation. Traditional fluid therapy was used in the control group in the intraoperative and postoperative period. The two groups were compared in terms of postoperative hemodynamic parameters, total fluid volume, incidence of adverse cardiac events, and recovery of bowel function. Compared with the control group, mean arterial pressure was significa