Efficacy of using VEGF165 gene in comprehensive treatment of patients with stage 2A-3 lower limb chronic ischaemia

• Published in: Angiologii͡a︡ i sosudistai͡a︡ khirurgii͡a Vol. 20; no. 2; p. 38
• Main Authors: Deev, R V, Bozo, I Ia, Mzhavanadze, N D, Nersesian, E G, Chukhralia, O V, Shval'b, P G, Cherviakov, Iu V, Staroverov, I N, Kalinin, R E, Voronov, D A, Gavrilenko, A V, Isaev, A A
• Format: Journal Article
• Language: Russian
• Published: Russia (Federation) 2014
• Subjects: Adult; Angiogenesis Inducing Agents - administration & dosage; Angiography; Ankle Brachial Index; Blood Flow Velocity - drug effects; Chronic Disease; Drug Monitoring - methods; Female; Genetic Therapy - methods; Humans; Injections, Intramuscular; Ischemia - drug therapy; Ischemia - etiology; Ischemia - physiopathology; Lower Extremity - blood supply; Male; Middle Aged; Neovascularization, Physiologic - drug effects; Oxygen Consumption - drug effects; Peripheral Arterial Disease - complications; Peripheral Arterial Disease - diagnosis; Peripheral Arterial Disease - drug therapy; Peripheral Arterial Disease - physiopathology; Regional Blood Flow - drug effects; Severity of Illness Index; Treatment Outcome; Vascular Endothelial Growth Factor A - administration & dosage

The authors share their experience in treating a total of 100 patients presenting with stage 2A-3 chronic lower limb ischaemia according to the classification of Pokrovsky-Fontain (the clinical group was composed of 75 patients and the control group comprised 25 subjects), in whom it was impossible...