A Case of Local Remnant Esophageal Cancer after Chemotherapy Getting Complete Response by Radiotherapy

• Published in: Gan to kagaku ryoho Vol. 47; no. 3; p. 510
• Main Authors: Takahashi, Kosuke, Sato, Shigeru, Ota, Yoshihiro, Watanabe, Takafumi, Tachibana, Shingo, Suda, Takeshi, Makuuchi, Yousuke, Iwasaki, Kenichi, Nagakawa, Yuichi, Osaka, Yoshiaki, Seshimo, Akiyoshi, Katsumata, Kenji, Tsuchida, Akihiko
• Format: Journal Article
• Language: Japanese
• Published: Japan 01.03.2020
• ISSN: 0385-0684

This is a case of a 72-year-old woman who presented without anymajor complaint. An anemia was indicated during follow-up for diabetes at the internal medicine unit and an upper gastrointestinal endoscopy(GS)was performed. A type 2 tumor was detected in the middle thoracic esophagus and biopsyrevealed a squamous cell carcinoma. A tumor was detected in the middle thoracic esophagus bycervical thoracoabdominal computed tomography(CT)scan and no invasion of surrounding organs was noted. The lymph node 104R had enlarged significantlybut no distant metastasis was observed. The patient was diagnosed with advanced esophageal cancer, Mt, type 2, cT2N2M0, stage Ⅱ. For preoperative chemotherapy, CDDP plus 5-FU(FP)therapywas administered. Lung metastasis was found on CT examination and surgical resection was not indicated. Hence, 4 courses of docetaxel plus CDDP plus 5-FU(DCF)therapywere administered. Following treatment, lung and lymph node metastases disappeared on the image. However, the main tumor remained at the GS. Radiotherapy was administered as a local additional treatment. Thereafter, GS showed mucous membrane redness and white spots of the lesion. Biopsyfrom the same site showed no malignant findings. The patient has remained malignancy-free since 18 months.