Embryo development potential after intracytoplasmic injection of sperm from azoospermia patients with different spermatogenic functions

To analyze the embryo development potential after intracytoplasmic injection of sperm from azoospermia patients with different spermatogenic functions. We performed ICSI with sperm retrieved from azoospermia patients with different spermatogenic functions using percutaneous epididymal sperm aspirati...

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Bibliographic Details
Published inZhonghua nan ke xue Vol. 18; no. 5; p. 432
Main Authors Qiu, Zhuo-Lin, Chu, Qing-Jun, Mao, Xiang-Ming, Luo, Chen, Quan, Song
Format Journal Article
LanguageChinese
Published China 01.05.2012
Subjects
Adult
Azoospermia - physiopathology
Azoospermia - therapy
Embryonic Development
Epididymis
Female
Humans
Male
Pregnancy
Pregnancy Rate
Sperm Injections, Intracytoplasmic
Sperm Retrieval
Spermatogenesis
Young Adult
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Summary:To analyze the embryo development potential after intracytoplasmic injection of sperm from azoospermia patients with different spermatogenic functions. We performed ICSI with sperm retrieved from azoospermia patients with different spermatogenic functions using percutaneous epididymal sperm aspiration (PESA) and testicular sperm aspiration (TESA). Then we recorded and analyzed the rates of normal fertilization, cleavages, excellent embryos and pregnancies. No statistically significant differences were found between the PESA and TESA groups in the rates of normal fertilization ([74.9 +/- 19.6] vs [66.3 +/- 22.7]%, P > 0.05), cleavages ([96.7 +/- 8.6] vs [92.8 +/- 19.8]%, P > 0.05), excellent embryos ([43.5 +/- 26.2] vs [35.0 +/- 29.4]%, P > 0.05) and pregnancies (44.0 vs 52.0%, P > 0.05). The normal fertilization rates in the patients with normal spermatogenesis, mild spermatogenic dysfunction (SD), moderate SD and severe SD were (77.8 +/- 18.4), (68.4 +/- 18.5), (73.5 +/- 19.8) and (51.4 +/- 27.9)%, respectiv
ISSN:1009-3591