Establishment of a rat model of low calcium diet related hyperoxaluria
To establish a rat model of low calcium diet related hyperoxaluria and explore its features. By means of randomized blocks design, totally 24 SD male rats were divided into low calcium diet group, medium calcium diet group, and high calcium diet group. Each group was sequentially fed on different ca...
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Published in | Zhōngguó yīxué kēxuéyuàn xuébào Vol. 34; no. 2; p. 134 |
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Main Authors | , , , , |
Format | Journal Article |
Language | Chinese |
Published |
China
01.04.2012
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Abstract | To establish a rat model of low calcium diet related hyperoxaluria and explore its features.
By means of randomized blocks design, totally 24 SD male rats were divided into low calcium diet group, medium calcium diet group, and high calcium diet group. Each group was sequentially fed on different calcium diets for 3 days. The urinary volume within 24 hours was recorded, the consistency of urinary oxalate by high-efficiency liquid chromatography, and the consistency of urine creatinine by automatic biochemical analyzer. The consistency was corrected to the output of urinary oxalate of rats in 24 hours, and the results were evaluated by repeated measurement of variance analysis and multivariate analysis of variance.
The output of urinary oxalate of rats in 24 hours varied with time (F=7.893, P0.05). The output of urinary oxalate of rats in 24 hours varied with group division (F=3.565, P<0.05). The output of urinary oxalate in 24 hours in three groups on the third day was significantly higher than that on the fi |
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AbstractList | To establish a rat model of low calcium diet related hyperoxaluria and explore its features.
By means of randomized blocks design, totally 24 SD male rats were divided into low calcium diet group, medium calcium diet group, and high calcium diet group. Each group was sequentially fed on different calcium diets for 3 days. The urinary volume within 24 hours was recorded, the consistency of urinary oxalate by high-efficiency liquid chromatography, and the consistency of urine creatinine by automatic biochemical analyzer. The consistency was corrected to the output of urinary oxalate of rats in 24 hours, and the results were evaluated by repeated measurement of variance analysis and multivariate analysis of variance.
The output of urinary oxalate of rats in 24 hours varied with time (F=7.893, P0.05). The output of urinary oxalate of rats in 24 hours varied with group division (F=3.565, P<0.05). The output of urinary oxalate in 24 hours in three groups on the third day was significantly higher than that on the fi |
Author | Sun, Xi-zhao Sun, Ze-yu Tian, Jing Guo, Hong-qian Lu, De-sheng |
Author_xml | – sequence: 1 givenname: Jing surname: Tian fullname: Tian, Jing organization: Nanjing University, Nanjing, China – sequence: 2 givenname: Hong-qian surname: Guo fullname: Guo, Hong-qian – sequence: 3 givenname: Xi-zhao surname: Sun fullname: Sun, Xi-zhao – sequence: 4 givenname: Ze-yu surname: Sun fullname: Sun, Ze-yu – sequence: 5 givenname: De-sheng surname: Lu fullname: Lu, De-sheng |
BackLink | https://www.ncbi.nlm.nih.gov/pubmed/22776598$$D View this record in MEDLINE/PubMed |
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Snippet | To establish a rat model of low calcium diet related hyperoxaluria and explore its features.
By means of randomized blocks design, totally 24 SD male rats were... |
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SubjectTerms | Animals Calcium Carbonate - administration & dosage Diet Disease Models, Animal Hyperoxaluria - etiology Hyperoxaluria - urine Male Rats Rats, Sprague-Dawley |
Title | Establishment of a rat model of low calcium diet related hyperoxaluria |
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