Management of COVID-19: the Zhejiang experience

• Published in: Zhejiang da xue xue bao. Journal of Zhejiang University. Medical sciences. Yi xue ban Vol. 49; no. 2; p. 147
• Main Authors: Xu, Kaijin, Cai, Hongliu, Shen, Yihong, Ni, Qin, Chen, Yu, Hu, Shaohua, Li, Jianping, Wang, Huafen, Yu, Liang, Huang, He, Qiu, Yunqing, Wei, Guoqing, Fang, Qiang, Zhou, Jianying, Sheng, Jifang, Liang, Tingbo, Li, Lanjuan
• Format: Journal Article
• Language: Chinese
• Published: China 25.05.2020
• Subjects: Betacoronavirus - isolation & purification; China - epidemiology; Coronavirus Infections - diagnosis; Coronavirus Infections - epidemiology; Coronavirus Infections - therapy; Coronavirus Infections - virology; COVID-19; Disease Management; Early Diagnosis; Feces - virology; Humans; Pandemics; Pneumonia, Viral - diagnosis; Pneumonia, Viral - epidemiology; Pneumonia, Viral - therapy; Pneumonia, Viral - virology; SARS-CoV-2; Sputum - virology; China
• ISSN: 1008-9292
• DOI: 10.3785/j.issn.1008-9292.2020.02.02

The current epidemic situation of coronavirus disease 2019 (COVID-19) still remained severe. As the National Clinical Research Center for Infectious Diseases, the First Affiliated Hospital of Zhejiang University School of Medicine is the primary medical care center for COVID-19 in Zhejiang province. Based on the present expert consensus carried out by National Health Commission and National Administration of Traditional Chinese Medicine, our team summarized and established an effective treatment strategy centered on "Four-Anti and Two-Balance" for clinical practice. The "Four-Anti and Two-Balance" strategy included antivirus, anti-shock, anti-hyoxemia, anti-secondary infection, and maintaining of water, electrolyte and acid base balance and microecological balance. Meanwhile, integrated multidisciplinary personalized treatment was recommended to improve therapeutic effect. The importance of early viralogical detection, dynamic monitoring of inflammatory indexes and chest radiograph was emphasized in clinical