Ukrain, a plant derived semi-synthetic compound, exerts antitumor effects against murine and human breast cancer and induce protective antitumor immunity in mice

• Published in: Experimental oncology Vol. 34; no. 4; p. 340
• Main Authors: Bozeman, E N, Srivatsan, S, Mohammadi, H, Daniels, D, Shashidharamurthy, R, Selvaraj, P
• Format: Journal Article
• Language: English
• Published: Ukraine 01.12.2012
• Subjects: Animals; Antineoplastic Agents - pharmacology; Apoptosis - drug effects; Berberine Alkaloids - pharmacology; Cell Line, Tumor; Cell Proliferation - drug effects; Cell Survival - drug effects; Female; Humans; Mammary Neoplasms, Experimental - drug therapy; Mammary Neoplasms, Experimental - immunology; Mice; Mice, Inbred BALB C; Phenanthridines - pharmacology; Phytotherapy - methods

Despite the recent advances in anti-cancer therapies, breast cancer accounts for the highest percentage of estimated new cases among female cancer patients. The anti-cancer drug Ukrain, a plant-derived semi-synthetic compound, has been shown to be effective in a variety of tumor models including col...