Thymosin β4 expression correlates with lymph node metastasis through hypoxia inducible factor-α induction in breast cancer
Intratumoral hypoxia has been correlated with distant metastatic potential. Two hypoxia inducible factors (HIFs), HIF-1α and HIF-2α, are induced by hypoxia, and high expression of these proteins has been correlated to angiogenesis and distant metastasis. Thymosin β4 (Tβ4) is frequently highly expres...
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Published in | Oncology reports Vol. 25; no. 1; pp. 23 - 31 |
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Main Authors | , , , , , , , , , , , , |
Format | Journal Article |
Language | English |
Published |
Greece
01.01.2011
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Subjects | |
Online Access | Get full text |
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