In vitro drug interactions of gallates with antibiotics in Staphylococcus Aureus

• Published in: Frontiers in bioscience (Elite edition) Vol. 2; no. 2; p. 668
• Main Authors: Soe, Win Mar, Tzer Pin Lin, Raymond, Chu Sing Lim, Lim, Sakharkar, Kishore R, Sakharkar, Meena K
• Format: Journal Article
• Language: English
• Published: Singapore 01.01.2010
• Subjects: Anti-Bacterial Agents - pharmacology; Catechin - analogs & derivatives; Catechin - pharmacology; Drug Interactions - physiology; Fusidic Acid; Gallic Acid - analogs & derivatives; Gallic Acid - pharmacology; In Vitro Techniques; Methicillin-Resistant Staphylococcus aureus - drug effects; Methicillin-Resistant Staphylococcus aureus - metabolism; Microbial Sensitivity Tests; Mupirocin; Tetracycline

The antimicrobial activities of tetracycline, mupirocin, and fusidic acid are tested in combination with Epicatechin Gallate (ECG), and Ethyl Gallate (EG) using 2 Methicillin resistant (MRSA) and 2 Methicillin sensitive (MSSA) strains of Staphylococcus aureus. Sub-inhibitory concentration of EG at 2...