Association study of HTR1A and HTR1B with adolescent idiopathic scoliosis

• Published in: Chung-hua wai kʿo tsa chih Vol. 48; no. 4; p. 296
• Main Authors: Wang, Hai, Wu, Zhi-hong, Zhuang, Qian-yu, Qiu, Gui-xing
• Format: Journal Article
• Language: Chinese
• Published: China 15.02.2010
• Subjects: Adolescent; Gene Frequency; Genetic Association Studies; Genotype; Humans; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Receptor, Serotonin, 5-HT1A - genetics; Receptor, Serotonin, 5-HT1B - genetics; Scoliosis - genetics

To assess whether HTR1A and HTR1B polymorphisms are associated with the predisposition, gender, PUMC Classification and/or severity of adolescent idiopathic scoliosis (AIS). Rs6294 (HTR1A) and rs6296 (HTR1B) were genotyped in 103 AIS patients treated from January 2006 to March 2007, and 108 controls...