A case of breast cancer with extensive osteonecrosis of maxilla induced by a bisphosphonate
Here, we report a case of extensive osteonecrosis of the maxilla associated with a history of bisphosphonate (BP) therapy for management of bone metastases from breast cancer. A 66-year-old woman was referred to our hospital because of a fistulation on the right side of the maxilla in May 2005 by he...
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Published in | Gan to kagaku ryoho Vol. 37; no. 4; p. 681 |
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Main Authors | , , , , , |
Format | Journal Article |
Language | Japanese |
Published |
Japan
01.04.2010
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Abstract | Here, we report a case of extensive osteonecrosis of the maxilla associated with a history of bisphosphonate (BP) therapy for management of bone metastases from breast cancer. A 66-year-old woman was referred to our hospital because of a fistulation on the right side of the maxilla in May 2005 by her dentist. The patient had a medical history of breast cancer with bone metastasis that was treated by chemotherapy with 45 mg pamidronate in 2 weekly courses for 16 months. We suspected that this rare case of osteonecrosis was caused by chemotherapy with BPs. Palliative treatments, including antibiotic therapy and local irrigation, were administered. Finally, extensive osteonecrosis of the maxilla occurred. |
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AbstractList | Here, we report a case of extensive osteonecrosis of the maxilla associated with a history of bisphosphonate (BP) therapy for management of bone metastases from breast cancer. A 66-year-old woman was referred to our hospital because of a fistulation on the right side of the maxilla in May 2005 by her dentist. The patient had a medical history of breast cancer with bone metastasis that was treated by chemotherapy with 45 mg pamidronate in 2 weekly courses for 16 months. We suspected that this rare case of osteonecrosis was caused by chemotherapy with BPs. Palliative treatments, including antibiotic therapy and local irrigation, were administered. Finally, extensive osteonecrosis of the maxilla occurred. |
Author | Inokuchi, Satoko Kusukawa, Jingo Yokomizo, Yuji Koga, Makoto Koga, Chihiro Tanaka, Yoshihiro |
Author_xml | – sequence: 1 givenname: Yoshihiro surname: Tanaka fullname: Tanaka, Yoshihiro organization: Dental and Oral Medical Center, Kurume University School of Medicine – sequence: 2 givenname: Makoto surname: Koga fullname: Koga, Makoto – sequence: 3 givenname: Yuji surname: Yokomizo fullname: Yokomizo, Yuji – sequence: 4 givenname: Satoko surname: Inokuchi fullname: Inokuchi, Satoko – sequence: 5 givenname: Chihiro surname: Koga fullname: Koga, Chihiro – sequence: 6 givenname: Jingo surname: Kusukawa fullname: Kusukawa, Jingo |
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SubjectTerms | Aged Antineoplastic Agents - adverse effects Antineoplastic Agents - therapeutic use Bone Neoplasms - diagnostic imaging Bone Neoplasms - drug therapy Bone Neoplasms - secondary Breast Neoplasms - drug therapy Diphosphonates - adverse effects Diphosphonates - therapeutic use Female Humans Maxillary Diseases - chemically induced Maxillary Diseases - diagnostic imaging Maxillary Diseases - pathology Maxillary Diseases - surgery Osteonecrosis - chemically induced Osteonecrosis - diagnostic imaging Osteonecrosis - pathology Osteonecrosis - surgery Palliative Care Tomography, X-Ray Computed |
Title | A case of breast cancer with extensive osteonecrosis of maxilla induced by a bisphosphonate |
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