Renal dysfunction and survival in hospitalized patients with chronic heart failure: a retrospective analysis

• Published in: Zhōnghuá xīnxuèguănbìng zázhì Vol. 37; no. 8; p. 729
• Main Authors: Yang, Yan-hua, Wang, Lin, An, Fang, Huang, Jiao-hong, Ma, Jin-ping, Li, Guang-ping, Li, Li-feng
• Format: Journal Article
• Language: Chinese
• Published: China 01.08.2009
• Subjects: Adult; Aged; Chronic Disease; Female; Heart Failure - diagnosis; Humans; Inpatients; Male; Middle Aged; Prognosis; Renal Insufficiency; Retrospective Studies; Survival Analysis
• ISSN: 0253-3758

To analyze the impact of renal dysfunction on survival in hospitalized chronic heart failure (CHF) patients. In this retrospective analysis, we collected all clinical data from eligible patients hospitalized in the second hospital of Tianjin Medical University between Jan 1980 and Aug 2007. CHF patients were divided into three groups according to glomerular filtration rate (GFR): A, normal renal function; B, mild renal dysfunction; C, renal dysfunction. Patients in group C were further divided into three subgroups according to hospitalization year: D, 1980.01 - 1989.12; E, 1990.01 - 1999.12; F, 2000.01 - 2007.08. Renal dysfunction was found in 714 patients. Compared with group A (n = 817) and group B (n = 928), patients in group C were older, had worse heart function and major medications included nitrates, diuretics and digitalis. From 1980 to 2007, use of Angiotensin II receptor antagonist, beta-blocker, statins significantly increased and the in-hospital mortality significantly decreased in group C patient