The role of ionic release from NovaMin (calcium sodium phosphosilicate) in tubule occlusion: an exploratory in vitro study using radio-labeled isotopes

• Published in: The Journal of clinical dentistry Vol. 21; no. 3; p. 72
• Main Authors: LaTorre, Guy, Greenspan, David C
• Format: Journal Article
• Language: English
• Published: United States 2010
• Subjects: Animals; Calcium Phosphates - analysis; Calcium Phosphates - pharmacokinetics; Calcium Radioisotopes - analysis; Cattle; Dentifrices - administration & dosage; Dentifrices - chemistry; Dentifrices - pharmacokinetics; Dentin - metabolism; Dentin - ultrastructure; Dentin Desensitizing Agents - administration & dosage; Dentin Desensitizing Agents - chemistry; Dentin Desensitizing Agents - pharmacokinetics; Dentin Permeability; Dose-Response Relationship, Drug; Glass; Neutron Activation Analysis; Particle Size; Phosphorus Radioisotopes - analysis; Porosity; Radiopharmaceuticals; Silicates - pharmacokinetics; Spectrometry, X-Ray Emission; Technetium Tc 99m Medronate

The primary objective of this work was to develop a method of quantifying the levels and source of calcium and phosphate deposited on dental hard tissue from a novel calcium phosphosilicate (NovaMin) material using neutron activation analysis (NAA). A second objective was to explore the utility of r...