Expression and its significance of Cyclin D1 in oral squamous cell carcinoma
To investigate the expression and significance of Cyclin D1 in oral squamous cell ma (OSCC). A immunohistochemistry method, Envosion, was employed to test the manifesting Cyclin D1 in pathological slices of 50 OSCC cases and 10 normal cases, and the results was treated with statistical lysis. In 50...
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| Published in | Hua xi kou qiang yi xue za zhi Vol. 29; no. 3; p. 299 |
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| Main Authors | , , , , , |
| Format | Journal Article |
| Language | Chinese |
| Published |
China
01.06.2011
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| Online Access | Get more information |
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| Abstract | To investigate the expression and significance of Cyclin D1 in oral squamous cell ma (OSCC).
A immunohistochemistry method, Envosion, was employed to test the manifesting Cyclin D1 in pathological slices of 50 OSCC cases and 10 normal cases, and the results was treated with statistical lysis.
In 50 OSCC cases, Cyclin D1 mainly manifested in karyon, and a little in cytoplasm. manifesting rates of Cyclin D1 in the samples was 80.0%, which was significantly higher than the manifesting of 20.0% in normal oral mucous membrane (P < 0.01). The manifestation of Cyclin D1 was correlated with rent pathological grades, clinical phases and lymph node metastasis (P < 0.05).
The abnormal tation of Cyclin D1 is closely related with the occurrence and development of OSCC. Therefore, it can subsidiary index for OSCC treatment and prognosis. |
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| AbstractList | To investigate the expression and significance of Cyclin D1 in oral squamous cell ma (OSCC).
A immunohistochemistry method, Envosion, was employed to test the manifesting Cyclin D1 in pathological slices of 50 OSCC cases and 10 normal cases, and the results was treated with statistical lysis.
In 50 OSCC cases, Cyclin D1 mainly manifested in karyon, and a little in cytoplasm. manifesting rates of Cyclin D1 in the samples was 80.0%, which was significantly higher than the manifesting of 20.0% in normal oral mucous membrane (P < 0.01). The manifestation of Cyclin D1 was correlated with rent pathological grades, clinical phases and lymph node metastasis (P < 0.05).
The abnormal tation of Cyclin D1 is closely related with the occurrence and development of OSCC. Therefore, it can subsidiary index for OSCC treatment and prognosis. |
| Author | He, Dong-Ning Li, Li-Hua Xing, Jin-Song Nan, Xin-Rong Shi, Pei-Rong Chen, Xian-Jiu |
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| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/21776860$$D View this record in MEDLINE/PubMed |
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| Snippet | To investigate the expression and significance of Cyclin D1 in oral squamous cell ma (OSCC).
A immunohistochemistry method, Envosion, was employed to test the... |
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| SubjectTerms | Carcinoma, Squamous Cell Cyclin D1 Female Humans Immunohistochemistry Lymphatic Metastasis Mouth Mucosa Mouth Neoplasms Prognosis |
| Title | Expression and its significance of Cyclin D1 in oral squamous cell carcinoma |
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