Ependymal/subventricular zone cells migrate to the peri-infarct region and differentiate into neurons and astrocytes after focal cerebral ischemia in adult rats

• Published in: Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA Vol. 25; no. 10; p. 1201
• Main Authors: Zhang, Peng-bo, Liu, Yong, Li, Jie, Kang, Qian-yan, Tian, Ying-fang, Chen, Xin-lin, Zhao, Jian-jun, Shi, Qin-dong, Song, Tu-sheng, Qian, Yi-hua
• Format: Journal Article
• Language: English
• Published: China 01.10.2005
• Subjects: Animals; Astrocytes - cytology; Cell Differentiation - physiology; Cell Movement; Cerebral Cortex - pathology; Corpus Callosum - pathology; Ependyma - cytology; Infarction, Middle Cerebral Artery - pathology; Lateral Ventricles - cytology; Male; Neurons - cytology; Rats; Rats, Sprague-Dawley

To investigate the migration and differentiation of ependymal/subventricular zone cells after focal cerebral ischemia in rats, and reveal the origin of the newly generated neural cells in the peri-infarct region. Normal adult male Sprague Dawley rats weighing 250-350 g were used in this study. Befor...