Experimental study of the use of piritramide as intrathecal analgesic

• Published in: Chirurgia (Bucharest, Romania : 1990) Vol. 102; no. 1; p. 57
• Main Authors: Tica, V I, Neştianu, V, Tica, A A, Beghim, M, Serbanescu, L, Beghim, Esra, Bafani, S
• Format: Journal Article
• Language: English; Romanian, Moldovan
• Published: Romania 01.01.2007
• Subjects: Analgesics, Opioid - pharmacology; Analgesics, Opioid - therapeutic use; Animals; Dogs; Injections, Spinal; Models, Animal; Pain - drug therapy; Pirinitramide - pharmacology; Pirinitramide - therapeutic use; Random Allocation; Respiration - drug effects

Opioids proved their advantages as general and intrathecal (i.t.) analgesics. Piritramide (P), a largely used analgesic opioid today, has not been studied in i.t. administration. Our experimental research aimed in determining the efficiency, security and optimal dose of i.t. P. In 9 adult mongrel do...