Imaging the serotonin transporter using (123)I-ADAM in the human brain

• Published in: Psychiatry research. Neuroimaging Vol. 172; no. 1; p. 38
• Main Authors: Chou, Yuan-Hwa, Yang, Bang-Hung, Chung, Ming-Yi, Chen, Shih-Pei, Su, Tung-Ping, Chen, Chia-Chieh, Wang, Shyh-Jen
• Format: Journal Article
• Language: English
• Published: Ireland 30.04.2009
• Subjects: Adult; Brain - diagnostic imaging; Brain - metabolism; Cinanserin - analogs & derivatives; Corpus Striatum - diagnostic imaging; Corpus Striatum - metabolism; Female; Humans; Image Interpretation, Computer-Assisted; Iodine Radioisotopes; Radioligand Assay; Receptor, Serotonin, 5-HT2A - metabolism; Serotonin Plasma Membrane Transport Proteins - metabolism; Tomography, Emission-Computed, Single-Photon

The aim of this study was to examine the feasibility of (123)I-ADAM to image the serotonin transporter (SERT) in Asian (Taiwanese) subjects. Single photon emission computed tomography (SPECT) scans were performed on nine healthy volunteers who were s-allele carriers at the polymorphism within the se...