Reduction of erythrocyte deformability in Krushinskiĭ-Molodkina rats in acute hemorrhagic cerebrovascular circulation disorders

The ability of erythrocytes to change their shapes in the shear flow under acute strokes of hemorrhagic type in rats of the Krushinsky-Molodkina line was studied. The rigidity of membranes and the internal viscosity of erythrocytes were investigated by the laser diffraction method. The method consis...

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Bibliographic Details
Published inBiofizika Vol. 51; no. 5; p. 833
Main Authors Priezzhev, A V, Lugovtsov, A E, Tiurina, A Iu, Koshelev, V B, Fadiukova, O E
Format Journal Article
LanguageRussian
Published Russia (Federation) 01.09.2006
Subjects
Acoustic Stimulation
Acute Disease
Animals
Brain - blood supply
Cerebrovascular Circulation
Erythrocyte Deformability
Female
Intracranial Hemorrhages - blood
Intracranial Hemorrhages - etiology
Intracranial Hemorrhages - physiopathology
Male
Rats
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Summary:The ability of erythrocytes to change their shapes in the shear flow under acute strokes of hemorrhagic type in rats of the Krushinsky-Molodkina line was studied. The rigidity of membranes and the internal viscosity of erythrocytes were investigated by the laser diffraction method. The method consists in obtaining diffraction images from a thin layer of a dilute suspension of erythrocytes moving in the shear flow and subsequent computer processing of these images. It was shown that strokes of hemorrhagical type in rats of the Krushinsky-Molodkina line cause a reduction in the ability of erythrocytes to change theirs shapes.
ISSN:0006-3029