Expression of a novel human retroviral NP9 gene and potential roles of its protein in systemic lupus erythematosus patients

• Published in: Zhonghua yi xue yi chuan xue za zhi Vol. 22; no. 3; p. 248
• Main Authors: Ren, Yue-zhong, Dai, Qiao-ding, Xu, Rong-zhen
• Format: Journal Article
• Language: English
• Published: China 01.06.2005
• Subjects: Amino Acid Sequence; Computational Biology; Endogenous Retroviruses - genetics; Endogenous Retroviruses - metabolism; Humans; Lupus Erythematosus, Systemic - genetics; Lupus Erythematosus, Systemic - physiopathology; Lupus Erythematosus, Systemic - virology; Molecular Sequence Data; Retroviridae Proteins - genetics; Retroviridae Proteins - metabolism; Retroviridae Proteins - physiology; Reverse Transcriptase Polymerase Chain Reaction

To investigate the expression of a novel retroviral (NP9) gene transcripts and the possible role of its protein in systemic lupus erythematosus (SLE) patients. The retroviral NP9 gene in SLE patients was isolated and cloned using RT-PCR and TA cloning techniques, and it was analyzed by sequencing. T...