Sleep and depression

Depression results in severe sleep disturbance. The "depressed brain" takes longer to initiate sleep, shortens the period to dreaming sleep, spends little or no time in "deep sleep" and is subject to hyperactive brain regions during sleep. Antidepressants rectify the sleep distur...

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Bibliographic Details
Published inMissouri medicine Vol. 103; no. 5; p. 526
Main Author Slaughter, James R
Format Journal Article
LanguageEnglish
Published United States 01.09.2006
Subjects
Depressive Disorder - complications
Depressive Disorder - physiopathology
Humans
Sleep Wake Disorders - etiology
Sleep Wake Disorders - physiopathology
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Summary:Depression results in severe sleep disturbance. The "depressed brain" takes longer to initiate sleep, shortens the period to dreaming sleep, spends little or no time in "deep sleep" and is subject to hyperactive brain regions during sleep. Antidepressants rectify the sleep disturbance and restore normal sleep architecture and presumably normal brain metabolism during sleep. Early intervention may lead to a decrease in neuronal cell loss due to depression, and better long-term outcomes for mood disorders.
ISSN:0026-6620