Coronary artery atherosclerotic plaque and stent visualizations by optical coherence tomography

• Published in: Zhōnghuá xīnxuèguănbìng zázhì Vol. 34; no. 2; p. 130
• Main Authors: Chen, Bu-xing, Ma, Feng-yun, Luo, Wei, Xie, Wen-li, Zhao, Xi-zhe, Sun, Shu-hong, Wang, Feng, Guo, Xu-mei, Chu, Xiao-wen
• Format: Journal Article
• Language: Chinese
• Published: China 01.02.2006
• Subjects: Adult; Aged; Coronary Disease - diagnostic imaging; Coronary Disease - therapy; Drug-Eluting Stents; Female; Follow-Up Studies; Humans; Male; Middle Aged; Radiography; Sirolimus - administration & dosage; Stents; Tomography, Optical Coherence
• ISSN: 0253-3758

To evaluate coronary artery atherosclerotic plaque characteristics and changes post coronary stenting by optical coherence tomography (OCT). OCT images were obtained in 22 diseased coronary vessels after coronary angiography or percutaneous coronary interventions (PCI) in 20 patients and in 23 stents [7 sirolimus-eluting stents (SES) follow up at 4-29 months post stenting and 8 bare mental stents (BMS) at 4-35 months post stenting, 8 stents immediately after PCI]. All 22 vessels and 23 stents OCT images were successfully acquired. Two thromboses, 8 fibrous, 9 lipid-rich and 3 calcium plaques as well as 3 plaque ruptures were visualized by OCT. No significant neointimal proliferation and restenosis were found in SES stents and some struts were not covered with neointima even at 29 months post stenting. Significant neointimal proliferation on surfaces of stent struts were visualized in all 8 BMS stents and restenosis was detected in 3 BMS stents. OCT images obtained immediately after PCI showed that 3 stents we