Lipoprotein (a) behaviour in patients with hepatocellular carcinoma

• Published in: Minerva medica Vol. 92; no. 5; p. 301
• Main Authors: Motta, M, Giugno, I, Ruello, P, Pistone, G, Di Fazio, I, Malaguarnera, M
• Format: Journal Article
• Language: English
• Published: Italy 01.10.2001
• Subjects: Aged; Alkaline Phosphatase - blood; alpha-Fetoproteins - analysis; Analysis of Variance; Carcinoma, Hepatocellular - blood; Cholesterol - blood; Cholesterol, HDL - blood; Cholesterol, LDL - blood; Data Interpretation, Statistical; Female; Ferritins - blood; Humans; Lipoprotein(a) - biosynthesis; Lipoprotein(a) - blood; Liver - metabolism; Liver Neoplasms - blood; Male; Middle Aged; Partial Thromboplastin Time; Risk Factors; Triglycerides - blood

Hepatocellular carcinoma (HCC) is a malignancy representing in Europe the 3-5% of all malignant tumors. Metabolic pathway of Lipoprotein(a) [Lp(a)] is influenced by various cytokines delivered during inflammatory and neoplastic diseases. Liver seems to be the main site of Lp(a) synthesis. A group of...