Genetics and colorectal cancer (HNPCC) in adolescence. A case report

• Published in: Revista do Hospital das Clinicás Vol. 53; no. 5; p. 257
• Main Authors: Nahas, S C, Borba, M R, Lourencao, J L, Nahas, C S, Lopes, L H
• Format: Journal Article
• Language: English
• Published: Brazil 01.09.1998
• Subjects: Adenocarcinoma - genetics; Adolescent; Colorectal Neoplasms, Hereditary Nonpolyposis - genetics; Female; Humans

The authors report a case of non-polyposis colon cancer in a seventeen year old female without prior polyposis or family history. Since it was the first case in this family, HNPCC was suspected. The polymerase chain reaction (PCR) of the tumor revealed changes in four polymorphic regions. Analysis o...