Treatment of complications after breast-conservation therapy
Over the past 2 decades, breast-conservation therapy with lumpectomy and whole-breast radiotherapy has become a standard option for the majority of women with newly diagnosed breast cancer. Long-term local control is achieved in approximately 85% of patients, and the therapy is generally well tolera...
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Published in | Oncology (Williston Park, N.Y.) Vol. 17; no. 8; p. 1118 |
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Main Authors | , , |
Format | Journal Article |
Language | English |
Published |
United States
01.08.2003
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Abstract | Over the past 2 decades, breast-conservation therapy with lumpectomy and whole-breast radiotherapy has become a standard option for the majority of women with newly diagnosed breast cancer. Long-term local control is achieved in approximately 85% of patients, and the therapy is generally well tolerated. There can, however, be long-term effects on the breast and other nearby tissues that may range from asymptomatic findings on examination to severe, debilitating problems. Infection, fat necrosis, and severe musculoskeletal problems such as osteoradionecrosis or soft-tissue necrosis are uncommon, affecting less than 5% of patients. However, changes in range of motion, mild-to-moderate musculoskeletal pain, and arm and breast edema are much more common. As more women choose breast-conservation therapy for management of their breast cancer, physicians will encounter these problems, as well as in-breast tumor recurrence, with greater frequency. This review will focus on the incidence, contributing factors, and management of the late problems of infection, fat necrosis, musculoskeletal complications, and local recurrence following breast-conservation therapy. |
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AbstractList | Over the past 2 decades, breast-conservation therapy with lumpectomy and whole-breast radiotherapy has become a standard option for the majority of women with newly diagnosed breast cancer. Long-term local control is achieved in approximately 85% of patients, and the therapy is generally well tolerated. There can, however, be long-term effects on the breast and other nearby tissues that may range from asymptomatic findings on examination to severe, debilitating problems. Infection, fat necrosis, and severe musculoskeletal problems such as osteoradionecrosis or soft-tissue necrosis are uncommon, affecting less than 5% of patients. However, changes in range of motion, mild-to-moderate musculoskeletal pain, and arm and breast edema are much more common. As more women choose breast-conservation therapy for management of their breast cancer, physicians will encounter these problems, as well as in-breast tumor recurrence, with greater frequency. This review will focus on the incidence, contributing factors, and management of the late problems of infection, fat necrosis, musculoskeletal complications, and local recurrence following breast-conservation therapy. |
Author | Frassica, Deborah A Bajaj, Gopal K Tsangaris, Theodore N |
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SubjectTerms | Abscess - etiology Abscess - therapy Breast Diseases - etiology Breast Diseases - therapy Breast Neoplasms - radiotherapy Breast Neoplasms - surgery Cellulitis - etiology Cellulitis - therapy Combined Modality Therapy Fat Necrosis - etiology Fat Necrosis - therapy Female Humans Mastectomy, Segmental Musculoskeletal Diseases - etiology Musculoskeletal Diseases - therapy Pain - drug therapy Pain - etiology Postoperative Complications - etiology Postoperative Complications - therapy Recurrence |
Title | Treatment of complications after breast-conservation therapy |
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