CT findings of pulmonary inflammatory pseudotumors (plasma cell granulomas)

• Published in: Nihon Igaku Hoshasen Gakkai zasshi. Nippon acta radiologica Vol. 54; no. 1; p. 13
• Main Authors: Kushihashi, T, Munechika, H, Satou, S, Ri, K, Seino, N, Ukisu, R, Motoya, H, Kurashita, Y, Hishida, T, Tanio, N
• Format: Journal Article
• Language: Japanese
• Published: Japan 25.01.1994
• Subjects: Adult; Aged; Aged, 80 and over; Child; Humans; Male; Plasma Cell Granuloma, Pulmonary - diagnostic imaging; Plasma Cell Granuloma, Pulmonary - pathology; Tomography, X-Ray Computed
• ISSN: 0048-0428

Pulmonary inflammatory pseudotumor (plasma cell granuloma) is not a true neoplastic lesion, but is composed of a variety of inflammatory cells, predominantly plasma cells. The chest X-ray features resemble those of malignant lung tumors; therefore, CT is often necessary for further evaluation. We report the CT features of five cases with histologically proved pulmonary inflammatory pseudotumor, which can be summarized as follows: a solitary round or oval parenchymal mass with regular or irregular margin, and with or without calcifications. The calcifications are useful for differential diagnosis if present, but they are usually non-specific in shape and configuration. The mean CT attenuation value of the major portion of the mass was increased from 41 HU to 78 HU by the injection of contrast material. In one case, a linear extension of the lesion was seen from the mass to the lung hilum. In three cases, satellite lung nodules were seen. One of these nodules was also proved histopathologically to be inflammatory pseudotumor. The biopsy specimens obtained by using a 20 gauge cutting-needle and an automated biopsy gun were satisfactory for histopathological diagnosis.